PROCAINE HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1954)
Entry Type: Small molecule
Molecule Category: Salt
UNII: 95URV01IDQ
Parent Compound: PROCAINE

Structure
InChI Key HCBIBCJNVBAKAB-UHFFFAOYSA-N
Smile CCN(CC)CCOC(=O)c1ccc(N)cc1.Cl
InChI
InChI=1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C13H21ClN2O2
Molecular Weight 272.78
AlogP 1.77
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 6.0
Polar Surface Area 55.56
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 17.0

Pharmacology

Action Mechanism of Action Reference
BLOCKER Sodium channel alpha subunit blocker ISBN PubMed PubMed PubMed Wikipedia
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
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Metabolites

visNetwork

Indications

Mesh Heading Maximum Phase Mesh ID Reference
HIV Infections 2 D015658 ClinicalTrials

Related Entries

Parent
Mixture
Mixture
Mixture
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Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Injury, poisoning and procedural complications
18.75
Blood and lymphatic system disorders
12.5
Gastrointestinal disorders
12.5
General disorders and administration site conditions
12.5
Musculoskeletal and connective tissue disorders
12.5
Vascular disorders
12.5
Hepatobiliary disorders
6.25
Investigations
6.25
Respiratory, thoracic and mediastinal disorders
6.25

Cross References

Resources Reference
ChEBI 8431
ChEMBL CHEMBL1200841
EPA CompTox DTXSID1044435
FDA SRS 95URV01IDQ
KEGG C07894
PubChem 5795
SureChEMBL SCHEMBL27720
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