Trade Names:
Synonyms:
Status: Approved (2008)
Entry Type: Protein
Molecule Category: UNKNOWN
ATC: B02BX04
UNII: GN5XU2DXKV

Pharmacology

Action Mechanism of Action Reference
AGONIST Thrombopoietin receptor agonist DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Purpura, Thrombocytopenic, Idiopathic 4 D016553 ClinicalTrials
Thrombocytopenia 4 D013921 ClinicalTrials
Lymphoma, Non-Hodgkin 2 D008228 ClinicalTrials
Anemia, Aplastic 2 D000741 ClinicalTrials
Myelodysplastic Syndromes 2 D009190 ClinicalTrials
Wiskott-Aldrich Syndrome 2 D014923 ClinicalTrials
Carcinoma 2 D002277 ClinicalTrials
Purpura, Thrombotic Thrombocytopenic 2 D011697 ClinicalTrials
Glioblastoma 2 D005909 ClinicalTrials
Ovarian Neoplasms 2 D010051 ClinicalTrials
Lymphoma 1 D008223 ClinicalTrials
Purpura, Thrombocytopenic 1 D011696 ClinicalTrials
Neoplasms 1 D009369 ClinicalTrials

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Investigations
11.34
Vascular disorders
10.61
General disorders and administration site conditions
9.12
Gastrointestinal disorders
7.53
Nervous system disorders
7.27
Respiratory, thoracic and mediastinal disorders
6.77
Blood and lymphatic system disorders
6.72
Injury, poisoning and procedural complications
6.04
Infections and infestations
5.99
Musculoskeletal and connective tissue disorders
5.61
Skin and subcutaneous tissue disorders
4.26
Metabolism and nutrition disorders
3.3
Cardiac disorders
2.69
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
2.29
Psychiatric disorders
2.05

Cross References

Resources Reference
CAS NUMBER 267639-76-9
ChEMBL CHEMBL1201832
FDA SRS GN5XU2DXKV
Guide to Pharmacology 6974
PubChem 66583167