ROPINIROLE HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1997)
Entry Type: Small molecule
Molecule Category: Salt
UNII: D7ZD41RZI9
Parent Compound: ROPINIROLE

Structure
InChI Key XDXHAEQXIBQUEZ-UHFFFAOYSA-N
Smile CCCN(CCC)CCc1cccc2c1CC(=O)N2.Cl
InChI
InChI=1S/C16H24N2O.ClH/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15;/h5-7H,3-4,8-12H2,1-2H3,(H,17,19);1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H25ClN2O
Molecular Weight 296.84
AlogP 2.85
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 7.0
Polar Surface Area 32.34
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 19.0

Pharmacology

Action Mechanism of Action Reference
AGONIST D2-like dopamine receptor agonist DailyMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 63

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Scaffolds

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Psychiatric disorders
20.58
Nervous system disorders
20.54
General disorders and administration site conditions
13.41
Injury, poisoning and procedural complications
6.83
Musculoskeletal and connective tissue disorders
6.75
Gastrointestinal disorders
5.15
Vascular disorders
3.37
Cardiac disorders
3.24
Respiratory, thoracic and mediastinal disorders
3.21
Skin and subcutaneous tissue disorders
2.22
Metabolism and nutrition disorders
2.18
Investigations
2.18

Cross References

Resources Reference
ChEBI 8889
ChEMBL CHEMBL1200411
EPA CompTox DTXSID50238533
FDA SRS D7ZD41RZI9
Guide to Pharmacology 7295
KEGG C07564
PubChem 68727
SureChEMBL SCHEMBL40760
ZINC ZINC00002041
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