SARGRAMOSTIM

Search structure
Trade Names:
Synonyms:
Status: Approved (1991)
Entry Type: Protein
Molecule Category: UNKNOWN
ATC: L03AA09
UNII: 5TAA004E22

Pharmacology

Action Mechanism of Action Reference
AGONIST Granulocyte-macrophage colony-stimulating factor receptor agonist PubMed DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Leukemia, Myeloid, Acute 4 D015470 ClinicalTrials
Leukemia, Myeloid, Acute 4 D015470 ClinicalTrials
Graft vs Host Disease 3 D006086 ClinicalTrials
Myelodysplastic Syndromes 3 D009190 ClinicalTrials
Urinary Bladder Neoplasms 3 D001749 ClinicalTrials
Breast Neoplasms 3 D001943 ClinicalTrials
Prostatic Neoplasms, Castration-Resistant 3 D064129 ClinicalTrials
Fever 3 D005334 ClinicalTrials
Melanoma 3 D008545 ClinicalTrials
Leishmaniasis, Cutaneous 3 D016773 ClinicalTrials
Lymphoma, Non-Hodgkin 3 D008228 ClinicalTrials
Cytomegalovirus Retinitis 3 D017726 ClinicalTrials
Leukemia 3 D007938 ClinicalTrials
Crohn Disease 3 D003424 ClinicalTrials
Leukemia, Myelogenous, Chronic, BCR-ABL Positive 3 D015464 ClinicalTrials
Neuroblastoma 3 D009447 ClinicalTrials
Hematologic Diseases 3 D006402 ClinicalTrials
Sepsis 3 D018805 ClinicalTrials
Mesenchymoma 3 D008637 ClinicalTrials
Infections 3 D007239 ClinicalTrials
Lymphoma 3 D008223 ClinicalTrials
Sarcoma 3 D012509 ClinicalTrials
Breast Neoplasms 3 D001943 ClinicalTrials
Breast Neoplasms 3 D001943 ClinicalTrials
Carcinoma, Renal Cell 3 D002292 ClinicalTrials
Neutropenia 3 D009503 ClinicalTrials
Melanoma 3 D008545 ClinicalTrials
Multiple Myeloma 3 D009101 ClinicalTrials
Pancreatic Neoplasms 3 D010190 ClinicalTrials
Melanoma 3 D008545 ClinicalTrials
Rhabdomyosarcoma 3 D012208 ClinicalTrials
Brain Neoplasms 2 D001932 ClinicalTrials
Cystadenoma, Serous 2 D018293 ClinicalTrials
Central Nervous System Neoplasms 2 D016543 ClinicalTrials
Rectal Neoplasms 2 D012004 ClinicalTrials
Myelodysplastic-Myeloproliferative Diseases 2 D054437 ClinicalTrials
Prostatic Neoplasms 2 D011471 ClinicalTrials
Pulmonary Alveolar Proteinosis 2 D011649 ClinicalTrials
Breast Neoplasms, Male 2 D018567 ClinicalTrials
Neoplasms 2 D009369 ClinicalTrials
Leukemia, Lymphocytic, Chronic, B-Cell 2 D015451 ClinicalTrials
HIV Infections 2 D015658 ClinicalTrials
Alzheimer Disease 2 D000544 ClinicalTrials
Burkitt Lymphoma 2 D002051 ClinicalTrials
Neoplasms 2 D009369 ClinicalTrials
Lymphoma, Large B-Cell, Diffuse 2 D016403 ClinicalTrials
Osteosarcoma 2 D012516 ClinicalTrials
Prostatic Neoplasms 2 D011471 ClinicalTrials
HIV Infections 2 D015658 ClinicalTrials
Ovarian Neoplasms 2 D010051 ClinicalTrials
Carcinoma, Non-Small-Cell Lung 2 D002289 ClinicalTrials
Kidney Diseases 2 D007674 ClinicalTrials
Biliary Tract Neoplasms 2 D001661 ClinicalTrials
Ovarian Neoplasms 2 D010051 ClinicalTrials
Peripheral Arterial Disease 2 D058729 ClinicalTrials
Inflammatory Breast Neoplasms 2 D058922 ClinicalTrials
Gliosarcoma 2 D018316 ClinicalTrials
Lymphoma, Mantle-Cell 2 D020522 ClinicalTrials
Colorectal Neoplasms 2 D015179 ClinicalTrials
Carcinoma, Endometrioid 2 D018269 ClinicalTrials
Glioblastoma 2 D005909 ClinicalTrials
Fallopian Tube Neoplasms 2 D005185 ClinicalTrials
Hodgkin Disease 2 D006689 ClinicalTrials
Carcinoma, Intraductal, Noninfiltrating 2 D002285 ClinicalTrials
Ganglioneuroblastoma 2 D018305 ClinicalTrials
Myeloproliferative Disorders 2 D009196 ClinicalTrials
Stomach Neoplasms 2 D013274 ClinicalTrials
Pulmonary Alveolar Proteinosis 2 D011649 ClinicalTrials
Peritoneal Neoplasms 2 D010534 ClinicalTrials
Fallopian Tube Neoplasms 2 D005185 ClinicalTrials
Kidney Neoplasms 2 D007680 ClinicalTrials
Gallbladder Neoplasms 2 D005706 ClinicalTrials
Esophageal Neoplasms 2 D004938 ClinicalTrials
Ovarian Neoplasms 2 D010051 ClinicalTrials
Lymphoma, Follicular 2 D008224 ClinicalTrials
Colonic Neoplasms 2 D003110 ClinicalTrials
Hematologic Neoplasms 2 D019337 ClinicalTrials
Squamous Cell Carcinoma of Head and Neck 2 D000077195 ClinicalTrials
Severe Acute Respiratory Syndrome 2 D045169 ClinicalTrials
Severe Acute Respiratory Syndrome 2 D045169 ClinicalTrials
Respiratory Distress Syndrome 2 D012128 ClinicalTrials
Colorectal Neoplasms 2 D015179 ClinicalTrials
Adenocarcinoma 1 D000230 ClinicalTrials
Leukemia, Plasma Cell 1 D007952 ClinicalTrials
Hepatitis B, Chronic 1 D019694 ClinicalTrials
Lung Neoplasms 1 D008175 ClinicalTrials
Anemia, Refractory, with Excess of Blasts 1 D000754 ClinicalTrials
Endometrial Neoplasms 1 D016889 ClinicalTrials
Arthritis, Rheumatoid 1 D001172 ClinicalTrials
Carcinoma, Hepatocellular 1 D006528 ClinicalTrials
Parkinson Disease 1 D010300 ClinicalTrials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 1 D054198 ClinicalTrials
Liver Neoplasms 1 D008113 ClinicalTrials
Triple Negative Breast Neoplasms 1 D064726 ClinicalTrials
Periodontitis 1 D010518 ClinicalTrials
Neoplasm Metastasis 1 D009362 ClinicalTrials
Glioma 1 D005910 ClinicalTrials
Myasthenia Gravis 0 D009157 ClinicalTrials

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
12.67
Metabolism and nutrition disorders
10.64
Gastrointestinal disorders
10.55
Investigations
8.79
Cardiac disorders
8.25
Nervous system disorders
7.71
Injury, poisoning and procedural complications
6.54
Musculoskeletal and connective tissue disorders
6.09
Respiratory, thoracic and mediastinal disorders
5.64
Skin and subcutaneous tissue disorders
5.37
Vascular disorders
4.82
Endocrine disorders
2.89

Cross References

Resources Reference
CAS NUMBER 123774-72-1
ChEMBL CHEMBL1201670
FDA SRS 5TAA004E22
Guide to Pharmacology 7905
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