SODIUM CHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved
Entry Type: Small molecule
Molecule Category: Salt
ATC: A12CA01
UNII: 451W47IQ8X

Structure
InChI Key FAPWRFPIFSIZLT-UHFFFAOYSA-M
Smile [Cl-].[Na+]
InChI
InChI=1S/ClH.Na/h1H;/q;+1/p-1

Physicochemical Descriptors

Property Name Value
Molecular Formula ClNa
Molecular Weight 58.44
AlogP None
Hydrogen Bond Acceptor None
Hydrogen Bond Donor None
Number of Rotational Bond None
Polar Surface Area None
Molecular species None
Aromatic Rings None
Heavy Atoms None

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetes Mellitus 4 D003920 ClinicalTrials
Heart Failure 4 D006333 ClinicalTrials
Common Cold 4 D003139 ClinicalTrials
Heart Failure 4 D006333 ClinicalTrials
Postoperative Nausea and Vomiting 3 D020250 ClinicalTrials
Hypotension 3 D007022 ClinicalTrials
Bronchiolitis 3 D001988 ClinicalTrials
Nasopharyngeal Neoplasms 3 D009303 ClinicalTrials
Bronchiectasis 3 D001987 ClinicalTrials
Parathyroid Diseases 3 D010279 ClinicalTrials
Hyponatremia 3 D007010 ClinicalTrials
Pre-Eclampsia 3 D011225 ClinicalTrials
Carcinoma, Non-Small-Cell Lung 3 D002289 ClinicalTrials
Myasthenia Gravis 3 D009157 ClinicalTrials
Pneumococcal Infections 3 D011008 ClinicalTrials
Wounds and Injuries 3 D014947 ClinicalTrials
Obesity 3 D009765 ClinicalTrials
Osteoarthritis 3 D010003 ClinicalTrials
Kidney Diseases 3 D007674 ClinicalTrials
Pain 3 D010146 ClinicalTrials
Acute Kidney Injury 3 D058186 ClinicalTrials
Cystic Fibrosis 3 D003550 ClinicalTrials
Myocardial Infarction 3 D009203 ClinicalTrials
Diabetes Mellitus, Type 1 3 D003922 ClinicalTrials
Diabetes Mellitus, Type 2 3 D003924 ClinicalTrials
Graft vs Host Disease 3 D006086 ClinicalTrials
Graves Ophthalmopathy 3 D049970 ClinicalTrials
Leiomyoma 3 D007889 ClinicalTrials
Melanoma 3 D008545 ClinicalTrials
Infections 3 D007239 ClinicalTrials
Infertility 3 D007246 ClinicalTrials
Schizophrenia 3 D012559 ClinicalTrials
Sjogren's Syndrome 3 D012859 ClinicalTrials
Stroke 3 D020521 ClinicalTrials
Malaria 3 D008288 ClinicalTrials
Obesity, Morbid 3 D009767 ClinicalTrials
Liver Cirrhosis 3 D008103 ClinicalTrials
Heart Diseases 3 D006331 ClinicalTrials
Multiple Sclerosis, Relapsing-Remitting 3 D020529 ClinicalTrials
Fractures, Bone 3 D050723 ClinicalTrials
Anemia 3 D000740 ClinicalTrials
Scoliosis 3 D012600 ClinicalTrials
Suicidal Ideation 3 D059020 ClinicalTrials
Rhinitis, Allergic, Seasonal 3 D006255 ClinicalTrials
Encephalitis, Japanese 3 D004672 ClinicalTrials
Otitis Media with Effusion 3 D010034 ClinicalTrials
Placenta Accreta 3 D010921 ClinicalTrials
Postpoliomyelitis Syndrome 3 D016262 ClinicalTrials
Sinusitis 3 D012852 ClinicalTrials
Hidradenitis Suppurativa 3 D017497 ClinicalTrials
Dry Eye Syndromes 3 D015352 ClinicalTrials
Bursitis 3 D002062 ClinicalTrials
Jaundice, Obstructive 3 D041781 ClinicalTrials
Cholecystitis, Acute 3 D041881 ClinicalTrials
Tendinopathy 3 D052256 ClinicalTrials
Tennis Elbow 3 D013716 ClinicalTrials
Fasciitis, Plantar 3 D036981 ClinicalTrials
Cleft Palate 3 D002972 ClinicalTrials
Constipation 3 D003248 ClinicalTrials
Headache 3 D006261 ClinicalTrials
Sepsis 3 D018805 ClinicalTrials
Ovarian Hyperstimulation Syndrome 3 D016471 ClinicalTrials
Telangiectasia, Hereditary Hemorrhagic 3 D013683 ClinicalTrials
Angioedemas, Hereditary 3 D054179 ClinicalTrials
Amyotrophic Lateral Sclerosis 3 D000690 ClinicalTrials
Atrial Fibrillation 3 D001281 ClinicalTrials
Crohn Disease 3 D003424 ClinicalTrials
Severe Acute Respiratory Syndrome 3 D045169 ClinicalTrials
Melanoma 3 D008545 ClinicalTrials
Bacterial Infections 3 D001424 ClinicalTrials
Coronary Disease 3 D003327 ClinicalTrials
Abscess 3 D000038 ClinicalTrials
Pneumonia 3 D011014 ClinicalTrials
Lung Diseases 3 D008171 ClinicalTrials
Infertility, Male 3 D007248 ClinicalTrials
Osteoarthritis, Knee 3 D020370 ClinicalTrials
Angioedema 3 D000799 ClinicalTrials
Shock, Septic 3 D012772 ClinicalTrials
Polymyalgia Rheumatica 3 D011111 ClinicalTrials
Rhinitis 3 D012220 ClinicalTrials
Delirium 3 D003693 ClinicalTrials
Postpartum Hemorrhage 3 D006473 ClinicalTrials
Rib Fractures 3 D012253 ClinicalTrials
Corneal Neovascularization 3 D016510 ClinicalTrials
Polycystic Kidney, Autosomal Dominant 3 D016891 ClinicalTrials
Renal Insufficiency 3 D051437 ClinicalTrials
Jaundice 3 D007565 ClinicalTrials
Deglutition Disorders 3 D003680 ClinicalTrials
Back Pain 3 D001416 ClinicalTrials
Chronic Pain 3 D059350 ClinicalTrials
Anemia, Sickle Cell 3 D000755 ClinicalTrials
Bronchopulmonary Dysplasia 3 D001997 ClinicalTrials
Alopecia 3 D000505 ClinicalTrials
Influenza, Human 3 D007251 ClinicalTrials
Pneumonia, Viral 3 D011024 ClinicalTrials
Hypoxia 3 D000860 ClinicalTrials
Osteoarthritis, Hip 3 D015207 ClinicalTrials
Periarthritis 3 D010489 ClinicalTrials
Pyelonephritis 3 D011704 ClinicalTrials
Raynaud Disease 3 D011928 ClinicalTrials
Scleroderma, Localized 3 D012594 ClinicalTrials
Renal Insufficiency 3 D051437 ClinicalTrials
Psychomotor Agitation 3 D011595 ClinicalTrials
Skin Abnormalities 3 D012868 ClinicalTrials
Anemia, Iron-Deficiency 3 D018798 ClinicalTrials
Joint Diseases 3 D007592 ClinicalTrials
Hypernatremia 3 D006955 ClinicalTrials
Low Back Pain 3 D017116 ClinicalTrials
Hypovolemia 3 D020896 ClinicalTrials
Laryngismus 3 D007826 ClinicalTrials
Shock 3 D012769 ClinicalTrials
Tendinopathy 3 D052256 ClinicalTrials
Breast Neoplasms 3 D001943 ClinicalTrials
Ovarian Neoplasms 3 D010051 ClinicalTrials
Prostatic Neoplasms, Castration-Resistant 3 D064129 ClinicalTrials
Graft vs Host Disease 3 D006086 ClinicalTrials
Brain Injuries 3 D001930 ClinicalTrials
Ischemic Stroke 3 D000083242 ClinicalTrials
Leiomyoma 3 D007889 ClinicalTrials
Bursitis 3 D002062 ClinicalTrials
Severe Acute Respiratory Syndrome 3 D045169 ClinicalTrials
Myocardial Infarction 3 D009203 ClinicalTrials
Bone Neoplasms 3 D001859 ClinicalTrials
Tennis Elbow 3 D013716 ClinicalTrials
Hypospadias 2 D007021 ClinicalTrials
Tuberculosis 2 D014376 ClinicalTrials
Restless Legs Syndrome 2 D012148 ClinicalTrials
Prader-Willi Syndrome 2 D011218 ClinicalTrials
Smoking Cessation 2 D016540 ClinicalTrials
Carcinoma, Hepatocellular 2 D006528 ClinicalTrials
Alzheimer Disease 2 D000544 ClinicalTrials
Asthma 2 D001249 ClinicalTrials
Neoplasms 2 D009369 ClinicalTrials
Cardiovascular Diseases 2 D002318 ClinicalTrials
Pulmonary Disease, Chronic Obstructive 2 D029424 ClinicalTrials
Cardiomyopathy, Dilated 2 D002311 ClinicalTrials
Glaucoma 2 D005901 ClinicalTrials
Glioblastoma 2 D005909 ClinicalTrials
Psoriasis 2 D011565 ClinicalTrials
Ischemia 2 D007511 ClinicalTrials
Adenomatous Polyposis Coli 2 D011125 ClinicalTrials
Psoriasis 2 D011565 ClinicalTrials
Abdominal Abscess 2 D018784 ClinicalTrials
Subarachnoid Hemorrhage 2 D013345 ClinicalTrials
Scleroderma, Systemic 2 D012595 ClinicalTrials
Colitis, Ulcerative 2 D003093 ClinicalTrials
Depressive Disorder, Major 2 D003865 ClinicalTrials
Tinnitus 2 D014012 ClinicalTrials
Aortic Aneurysm 2 D001014 ClinicalTrials
Parkinson Disease 2 D010300 ClinicalTrials
Reperfusion Injury 2 D015427 ClinicalTrials
Acute Lung Injury 2 D055371 ClinicalTrials
Child Development Disorders, Pervasive 2 D002659 ClinicalTrials
Myopia 2 D009216 ClinicalTrials
Hypersensitivity 2 D006967 ClinicalTrials
Alcoholism 2 D000437 ClinicalTrials
Vaginosis, Bacterial 2 D016585 ClinicalTrials
Hip Fractures 2 D006620 ClinicalTrials
Severe Dengue 2 D019595 ClinicalTrials
Dupuytren Contracture 2 D004387 ClinicalTrials
Erectile Dysfunction 2 D007172 ClinicalTrials
Obsessive-Compulsive Disorder 2 D009771 ClinicalTrials
Arrhythmias, Cardiac 2 D001145 ClinicalTrials
West Nile Fever 2 D014901 ClinicalTrials
Aortic Aneurysm, Thoracic 2 D017545 ClinicalTrials
Colonic Neoplasms 2 D003110 ClinicalTrials
Intervertebral Disc Displacement 2 D007405 ClinicalTrials
Cerebral Hemorrhage 2 D002543 ClinicalTrials
Gastrointestinal Hemorrhage 2 D006471 ClinicalTrials
Head and Neck Neoplasms 2 D006258 ClinicalTrials
Conjunctivitis, Allergic 2 D003233 ClinicalTrials
Appendicitis 2 D001064 ClinicalTrials
Hemorrhagic Fever, Ebola 2 D019142 ClinicalTrials
Herpes Genitalis 2 D006558 ClinicalTrials
Heart Septal Defects, Ventricular 2 D006345 ClinicalTrials
Periodontal Diseases 2 D010510 ClinicalTrials
Liver Neoplasms 2 D008113 ClinicalTrials
Respiratory Distress Syndrome 2 D012128 ClinicalTrials
Lymphedema 2 D008209 ClinicalTrials
Pulmonary Edema 2 D011654 ClinicalTrials
Myelodysplastic Syndromes 2 D009190 ClinicalTrials
Virus Diseases 2 D014777 ClinicalTrials
Diabetic Foot 2 D017719 ClinicalTrials
Acromegaly 2 D000172 ClinicalTrials
Neoplasms 2 D009369 ClinicalTrials
Stomatitis 2 D013280 ClinicalTrials
Stress Disorders, Post-Traumatic 2 D013313 ClinicalTrials
Takotsubo Cardiomyopathy 2 D054549 ClinicalTrials
Hypoglycemia 2 D007003 ClinicalTrials
Xerostomia 2 D014987 ClinicalTrials
Varicose Veins 2 D014648 ClinicalTrials
Myalgia 2 D063806 ClinicalTrials
Sciatica 2 D012585 ClinicalTrials
Cough 2 D003371 ClinicalTrials
Skin Ulcer 2 D012883 ClinicalTrials
Kartagener Syndrome 2 D007619 ClinicalTrials
Frontotemporal Dementia 2 D057180 ClinicalTrials
Familial Mediterranean Fever 2 D010505 ClinicalTrials
Lung Neoplasms 2 D008175 ClinicalTrials
Meningitis 2 D008581 ClinicalTrials
HIV Infections 2 D015658 ClinicalTrials
Dementia 2 D003704 ClinicalTrials
HIV Infections 2 D015658 ClinicalTrials
Brain Neoplasms 2 D001932 ClinicalTrials
Varicose Ulcer 2 D014647 ClinicalTrials
Prostatic Hyperplasia 2 D011470 ClinicalTrials
Bipolar Disorder 2 D001714 ClinicalTrials
Hepatitis B, Chronic 2 D019694 ClinicalTrials
Ascites 2 D001201 ClinicalTrials
Macular Degeneration 2 D008268 ClinicalTrials
Compartment Syndromes 2 D003161 ClinicalTrials
Hepatitis C 2 D006526 ClinicalTrials
Peripheral Nervous System Diseases 2 D010523 ClinicalTrials
Tremor 2 D014202 ClinicalTrials
Renal Insufficiency, Chronic 2 D051436 ClinicalTrials
Multiple Sclerosis 2 D009103 ClinicalTrials
Acne Vulgaris 2 D000152 ClinicalTrials
Carpal Tunnel Syndrome 2 D002349 ClinicalTrials
Glaucoma, Open-Angle 2 D005902 ClinicalTrials
Eosinophilic Esophagitis 2 D057765 ClinicalTrials
Cocaine-Related Disorders 2 D019970 ClinicalTrials
Death, Sudden, Cardiac 2 D016757 ClinicalTrials
Esophageal Achalasia 2 D004931 ClinicalTrials
Anxiety 2 D001007 ClinicalTrials
Depressive Disorder 2 D003866 ClinicalTrials
Dysentery, Bacillary 2 D004405 ClinicalTrials
Fibromyalgia 2 D005356 ClinicalTrials
Neonatal Abstinence Syndrome 2 D009357 ClinicalTrials
Cicatrix 2 D002921 ClinicalTrials
Cataract 2 D002386 ClinicalTrials
Hypotrichosis 2 D007039 ClinicalTrials
Liver Failure, Acute 2 D017114 ClinicalTrials
Multiple Sclerosis, Chronic Progressive 2 D020528 ClinicalTrials
Urinary Bladder Neoplasms 2 D001749 ClinicalTrials
Non-ST Elevated Myocardial Infarction 2 D000072658 ClinicalTrials
Intervertebral Disc Degeneration 2 D055959 ClinicalTrials
Blood Coagulation Disorders 2 D001778 ClinicalTrials
Heart Arrest 2 D006323 ClinicalTrials
Burns 2 D002056 ClinicalTrials
Headache Disorders 2 D020773 ClinicalTrials
Macular Degeneration 2 D008268 ClinicalTrials
Urethral Stricture 2 D014525 ClinicalTrials
Rectal Neoplasms 2 D012004 ClinicalTrials
Rosacea 2 D012393 ClinicalTrials
Colonic Neoplasms 2 D003110 ClinicalTrials
Lung Diseases, Interstitial 2 D017563 ClinicalTrials
Inflammation 2 D007249 ClinicalTrials
Glaucoma, Neovascular 2 D015355 ClinicalTrials
Respiratory Distress Syndrome 2 D012128 ClinicalTrials
Pulpitis 2 D011671 ClinicalTrials
Leukemia, Myeloid, Acute 2 D015470 ClinicalTrials
Multiple Organ Failure 2 D009102 ClinicalTrials
Mycosis Fungoides 1 D009182 ClinicalTrials
Pruritus 1 D011537 ClinicalTrials
Papilloma 1 D010212 ClinicalTrials
Lyme Disease 1 D008193 ClinicalTrials
Substance-Related Disorders 1 D019966 ClinicalTrials
Persistent Fetal Circulation Syndrome 1 D010547 ClinicalTrials
Nausea 1 D009325 ClinicalTrials
Dyspnea 1 D004417 ClinicalTrials
Cognitive Dysfunction 1 D060825 ClinicalTrials
Digestive System Diseases 1 D004066 ClinicalTrials
Dengue 1 D003715 ClinicalTrials
Dental Caries 1 D003731 ClinicalTrials
Streptococcal Infections 1 D013290 ClinicalTrials
Tachycardia, Ventricular 1 D017180 ClinicalTrials
Postoperative Complications 1 D011183 ClinicalTrials
Fever 1 D005334 ClinicalTrials
Diphtheria 1 D004165 ClinicalTrials
Renal Colic 1 D056844 ClinicalTrials
Insulin Resistance 1 D007333 ClinicalTrials
Gastroenteritis 1 D005759 ClinicalTrials
Glycogen Storage Disease Type II 1 D006009 ClinicalTrials
Status Asthmaticus 1 D013224 ClinicalTrials
Herpes Zoster 1 D006562 ClinicalTrials
Mucopolysaccharidoses 1 D009083 ClinicalTrials
Clostridium Infections 1 D003015 ClinicalTrials
Muscular Dystrophy, Duchenne 1 D020388 ClinicalTrials
Skin Diseases 1 D012871 ClinicalTrials
Substance-Related Disorders 1 D019966 ClinicalTrials
Hypogonadism 1 D007006 ClinicalTrials
Hyperhidrosis 1 D006945 ClinicalTrials
Hodgkin Disease 1 D006689 ClinicalTrials
Hypertension, Pulmonary 1 D006976 ClinicalTrials
Prediabetic State 1 D011236 ClinicalTrials
Zika Virus Infection 1 D000071243 ClinicalTrials
Neuroma 1 D009463 ClinicalTrials
Hypertension 1 D006973 ClinicalTrials
Brain Concussion 1 D001924 ClinicalTrials
Aging 1 D000375 ClinicalTrials
Down Syndrome 1 D004314 ClinicalTrials
Nutrition Disorders 1 D009748 ClinicalTrials
Pseudomonas Infections 1 D011552 ClinicalTrials
Respiratory Insufficiency 1 D012131 ClinicalTrials
Arthritis, Rheumatoid 1 D001172 ClinicalTrials
Striae Distensae 1 D057896 ClinicalTrials
Heavy Metal Poisoning 1 D000075322 ClinicalTrials
Kidney Tubular Necrosis, Acute 1 D007683 ClinicalTrials
Clostridium Infections 1 D003015 ClinicalTrials
Tobacco Use Disorder 1 D014029 ClinicalTrials
Ductus Arteriosus, Patent 1 D004374 ClinicalTrials
Intermittent Claudication 1 D007383 ClinicalTrials
Pneumonia, Pneumococcal 1 D011018 ClinicalTrials
Orthomyxoviridae Infections 1 D009976 ClinicalTrials
Familial Primary Pulmonary Hypertension 1 D065627 ClinicalTrials
Aortic Coarctation 1 D001017 ClinicalTrials
Acquired Immunodeficiency Syndrome 1 D000163 ClinicalTrials
Essential Hypertension 1 D000075222 ClinicalTrials
Opioid-Related Disorders 0 D009293 ClinicalTrials
Phobia, Social 0 D000072861 ClinicalTrials
Peripheral Arterial Disease 0 D058729 ClinicalTrials
Hyperinsulinism 0 D006946 ClinicalTrials
Neuralgia 0 D009437 ClinicalTrials
Brain Edema 0 D001929 ClinicalTrials
Pancreatic Neoplasms 0 D010190 ClinicalTrials

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Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
14.02
Vascular disorders
8.31
Cardiac disorders
7.48
Blood and lymphatic system disorders
6.96
Respiratory, thoracic and mediastinal disorders
6.89
Injury, poisoning and procedural complications
6.78
Nervous system disorders
6.13
Skin and subcutaneous tissue disorders
5.95
Metabolism and nutrition disorders
5.5
Gastrointestinal disorders
5.19
Renal and urinary disorders
4.23
Investigations
4.05
Infections and infestations
4.03
Musculoskeletal and connective tissue disorders
3.06
Psychiatric disorders
2.55
Immune system disorders
2.54

Cross References

Resources Reference
CAS NUMBER 7647-14-5
ChEBI 26710
ChEMBL CHEMBL1200574
DrugBank DB09153
EPA CompTox DTXSID3021271
FDA SRS 451W47IQ8X
KEGG C13563
PubChem 5234
SureChEMBL SCHEMBL608
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