TAPENTADOL HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (2008)
Entry Type: Small molecule
Molecule Category: Salt
UNII: 71204KII53
Parent Compound: TAPENTADOL

Structure
InChI Key ZELFLGGRLLOERW-YECZQDJWSA-N
Smile CC[C@@H](c1cccc(O)c1)[C@@H](C)CN(C)C.Cl
InChI
InChI=1S/C14H23NO.ClH/c1-5-14(11(2)10-15(3)4)12-7-6-8-13(16)9-12;/h6-9,11,14,16H,5,10H2,1-4H3;1H/t11-,14+;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C14H24ClNO
Molecular Weight 257.81
AlogP 3.08
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 23.47
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 16.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Mu opioid receptor agonist DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Pain 4 D010146 ClinicalTrials
Low Back Pain 3 D017116 ClinicalTrials

Related Entries

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
17.75
Nervous system disorders
15.32
Psychiatric disorders
14.46
Injury, poisoning and procedural complications
10.25
Gastrointestinal disorders
8.15
Musculoskeletal and connective tissue disorders
3.92
Cardiac disorders
3.79
Vascular disorders
3.59
Respiratory, thoracic and mediastinal disorders
3.56
Investigations
3.41
Skin and subcutaneous tissue disorders
3.09
Metabolism and nutrition disorders
2.08

Cross References

Resources Reference
ChEMBL CHEMBL1201777
FDA SRS 71204KII53
KEGG D06007
PubChem 9838021
SureChEMBL SCHEMBL17104708
ZINC ZINC00020783
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