TETRACAINE HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (2016)
Entry Type: Small molecule
Molecule Category: Salt
UNII: 5NF5D4OPCI
Parent Compound: TETRACAINE

Structure
InChI Key PPWHTZKZQNXVAE-UHFFFAOYSA-N
Smile CCCCNc1ccc(C(=O)OCCN(C)C)cc1.Cl
InChI
InChI=1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C15H25ClN2O2
Molecular Weight 300.83
AlogP 2.62
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 8.0
Polar Surface Area 41.57
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 19.0

Pharmacology

Action Mechanism of Action Reference
BLOCKER Sodium channel alpha subunit blocker
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Transferase
- - - - 29.79
Epigenetic regulator Eraser Histone deacetylase HDAC class IIb
- - - - -36.11--0.61
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 61.91

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Parent
Mixture

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Eye disorders
80.0
General disorders and administration site conditions
20.0

Cross References

Resources Reference
ChEBI 9469
ChEMBL CHEMBL1255654
EPA CompTox DTXSID6042448
FDA SRS 5NF5D4OPCI
PubChem 16057735
SureChEMBL SCHEMBL24370
CONTENTS