| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1963) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt |
| UNII: | T5IRO3534A |
| Parent Compound: | VINCRISTINE |
Structure
| InChI Key | AQTQHPDCURKLKT-JKDPCDLQSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value | |
|---|---|---|
| Molecular Formula | C46H58N4O14S | |
| Molecular Weight | 923.05 | |
| AlogP | 3.52 | |
| Hydrogen Bond Acceptor | 12.0 | |
| Hydrogen Bond Donor | 3.0 | |
| Number of Rotational Bond | 8.0 | |
| Polar Surface Area | 171.17 | |
| Molecular species | BASE | |
| Aromatic Rings | 3.0 | |
| Heavy Atoms | 60.0 |
Pharmacology
Metabolites
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference | ||
|---|---|---|---|---|---|
| Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | 3 | D054218 | ClinicalTrials | ||
| Brain Neoplasms | 3 | D001932 | ClinicalTrials | ||
| Astrocytoma | 3 | D001254 | ClinicalTrials | ||
| Sarcoma, Kaposi | 3 | D012514 | ClinicalTrials | ||
| Central Nervous System Neoplasms | 3 | D016543 | ClinicalTrials | ||
| Mesenchymoma | 3 | D008637 | ClinicalTrials | ||
| Precursor Cell Lymphoblastic Leukemia-Lymphoma | 3 | D054198 | ClinicalTrials | ||
| Precursor Cell Lymphoblastic Leukemia-Lymphoma | 3 | D054198 | ClinicalTrials | ||
| Kidney Neoplasms | 3 | D007680 | ClinicalTrials | ||
| Uterine Cervical Neoplasms | 3 | D002583 | ClinicalTrials | ||
| Lung Neoplasms | 3 | D008175 | ClinicalTrials | ||
| Hodgkin Disease | 3 | D006689 | ClinicalTrials | ||
| Lymphoma, Follicular | 3 | D008224 | ClinicalTrials | ||
| Leukemia-Lymphoma, Adult T-Cell | 3 | D015459 | ClinicalTrials | ||
| Precursor Cell Lymphoblastic Leukemia-Lymphoma | 3 | D054198 | ClinicalTrials | ||
| Leukemia, Biphenotypic, Acute | 3 | D015456 | ClinicalTrials | ||
| Leukemia, Lymphocytic, Chronic, B-Cell | 3 | D015451 | ClinicalTrials | ||
| Lymphoma, Follicular | 3 | D008224 | ClinicalTrials | ||
| Hodgkin Disease | 3 | D006689 | ClinicalTrials | ||
| Leukemia, Biphenotypic, Acute | 3 | D015456 | ClinicalTrials | ||
| Lymphoma, T-Cell, Peripheral | 3 | D016411 | ClinicalTrials | ||
| Rhabdomyosarcoma, Alveolar | 3 | D018232 | ClinicalTrials | ||
| Carcinoma | 3 | D002277 | ClinicalTrials | ||
| Lymphoma, Large B-Cell, Diffuse | 3 | D016403 | ClinicalTrials | ||
| Rhabdomyosarcoma, Embryonal | 3 | D018233 | ClinicalTrials | ||
| Leukemia | 3 | D007938 | ClinicalTrials | ||
| Lymphoma | 3 | D008223 | ClinicalTrials | ||
| Mesothelioma | 3 | D008654 | ClinicalTrials | ||
| Neoplasms | 3 | D009369 | ClinicalTrials | ||
| Neuroblastoma | 3 | D009447 | ClinicalTrials | ||
| Sarcoma | 3 | D012509 | ClinicalTrials | ||
| Multiple Myeloma | 3 | D009101 | ClinicalTrials | ||
| Rhabdomyosarcoma | 3 | D012208 | ClinicalTrials | ||
| Medulloblastoma | 3 | D008527 | ClinicalTrials | ||
| Neuroectodermal Tumors, Primitive | 3 | D018242 | ClinicalTrials | ||
| Lymphoma, Non-Hodgkin | 3 | D008228 | ClinicalTrials | ||
| Head and Neck Neoplasms | 3 | D006258 | ClinicalTrials | ||
| Hepatoblastoma | 3 | D018197 | ClinicalTrials | ||
| Lymphoma, Mantle-Cell | 3 | D020522 | ClinicalTrials | ||
| Colorectal Neoplasms | 3 | D015179 | ClinicalTrials | ||
| Wilms Tumor | 3 | D009396 | ClinicalTrials | ||
| Retinoblastoma | 3 | D012175 | ClinicalTrials | ||
| Lymphoma, Large-Cell, Anaplastic | 2 | D017728 | ClinicalTrials | ||
| Leukemia, Myeloid, Acute | 2 | D015470 | ClinicalTrials | ||
| Lymphoma, AIDS-Related | 2 | D016483 | ClinicalTrials | ||
| Burkitt Lymphoma | 2 | D002051 | ClinicalTrials | ||
| Neuroectodermal Tumors, Primitive, Peripheral | 2 | D018241 | ClinicalTrials | ||
| Neurofibromatosis 1 | 2 | D009456 | ClinicalTrials | ||
| Blast Crisis | 2 | D001752 | ClinicalTrials | ||
| Sarcoma, Ewing | 2 | D012512 | ClinicalTrials | ||
| Acquired Immunodeficiency Syndrome | 2 | D000163 | ClinicalTrials | ||
| Lymphohistiocytosis, Hemophagocytic | 2 | D051359 | ClinicalTrials | ||
| Leukemia, Lymphoid | 1 | D007945 | ClinicalTrials | ||
| Hematologic Diseases | 1 | D006402 | ClinicalTrials | ||
| Melanoma | 1 | D008545 | ClinicalTrials | ||
| Waldenstrom Macroglobulinemia | 1 | D008258 | ClinicalTrials |
Related Entries
Scaffolds
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 79401 |
| ChEMBL | CHEMBL501867 |
| EPA CompTox | DTXSID8044331 |
| FDA SRS | T5IRO3534A |
| KEGG | C13974 |
| PubChem | 5388992 |
| SureChEMBL | SCHEMBL3710 |
| ZINC | ZINC85537024 |
CONTENTS