ADIPIPLON

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: OPL214POJ1

Structure
InChI Key UAMAIHOEGLEXSV-UHFFFAOYSA-N
Smile CCCc1c(Cn2ccnc2-c2ncccc2F)ncn2nc(C)nc12
InChI
InChI=1S/C18H18FN7/c1-3-5-13-15(22-11-26-17(13)23-12(2)24-26)10-25-9-8-21-18(25)16-14(19)6-4-7-20-16/h4,6-9,11H,3,5,10H2,1-2H3

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H18FN7
Molecular Weight 351.39
AlogP 2.83
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 5.0
Polar Surface Area 73.79
Molecular species NEUTRAL
Aromatic Rings 4.0
Heavy Atoms 26.0

Pharmacology

Action Mechanism of Action Reference
PARTIAL AGONIST GABA-A receptor; anion channel partial agonist Wikipedia Other

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Sleep Initiation and Maintenance Disorders 2 D007319 ClinicalTrials

Cross References

Resources Reference
CAS NUMBER 840486-93-3
ChEMBL CHEMBL2103791
DrugBank DB06579
EPA CompTox DTXSID40232944
FDA SRS OPL214POJ1
PubChem 11198924
SureChEMBL SCHEMBL4543571
ZINC ZINC000030691732
CONTENTS