| Synonyms: | |
| Status: | Approved (2018) |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| ATC: | B02BX08 |
| UNII: | 3H8GSZ4SQL |
Structure
| InChI Key | OFZJKCQENFPZBH-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C29H34Cl2N6O3S2 |
| Molecular Weight | 649.67 |
| AlogP | 6.58 |
| Hydrogen Bond Acceptor | 9.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 7.0 |
| Polar Surface Area | 101.9 |
| Molecular species | ACID |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 42.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| AGONIST | Thrombopoietin receptor agonist | PubMed |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Liver Diseases | 3 | D008107 | ClinicalTrials |
| Purpura, Thrombocytopenic, Idiopathic | 3 | D016553 | ClinicalTrials |
| Thrombocytopenia | 3 | D013921 | ClinicalTrials |
| Blood Platelet Disorders | 2 | D001791 | ClinicalTrials |
| Anemia, Aplastic | 2 | D000741 | ClinicalTrials |
Related Entries
MCS
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 570406-98-3 |
| ChEMBL | CHEMBL2103883 |
| DrugBank | DB11995 |
| DrugCentral | 5285 |
| EPA CompTox | DTXSID30205667 |
| FDA SRS | 3H8GSZ4SQL |
| Guide to Pharmacology | 9953 |
| PubChem | 9852519 |
| SureChEMBL | SCHEMBL289354 |
| ZINC | ZINC000072190218 |
CONTENTS