AZELNIDIPINE

Search structure
Synonyms:
Status: Approved
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: PV23P19YUG

Structure
InChI Key ZKFQEACEUNWPMT-UHFFFAOYSA-N
Smile CC1=C(C(=O)OC(C)C)C(c2cccc([N+](=O)[O-])c2)C(C(=O)OC2CN(C(c3ccccc3)c3ccccc3)C2)=C(N)N1
InChI
InChI=1S/C33H34N4O6/c1-20(2)42-32(38)27-21(3)35-31(34)29(28(27)24-15-10-16-25(17-24)37(40)41)33(39)43-26-18-36(19-26)30(22-11-6-4-7-12-22)23-13-8-5-9-14-23/h4-17,20,26,28,30,35H,18-19,34H2,1-3H3

Physicochemical Descriptors

Property Name Value
Molecular Formula C33H34N4O6
Molecular Weight 582.66
AlogP 4.69
Hydrogen Bond Acceptor 9.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 9.0
Polar Surface Area 137.03
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 43.0

Pharmacology

Action Mechanism of Action Reference
BLOCKER Voltage-gated L-type calcium channel blocker PubMed PubMed PubMed PubMed

Indications

Mesh Heading Maximum Phase Reference
Cerebral Small Vessel Diseases Phase 4 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 123524-52-7
ChEBI 31247
ChEMBL CHEMBL1275868
DrugBank DB09230
DrugCentral 272
EPA CompTox DTXSID3020120
FDA SRS PV23P19YUG
PubChem 65948
SureChEMBL SCHEMBL49021
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