BRINCIDOFOVIR

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 6794O900AX

Structure
InChI Key WXJFKKQWPMNTIM-VWLOTQADSA-N
Smile CCCCCCCCCCCCCCCCOCCCOP(=O)(O)CO[C@H](CO)Cn1ccc(N)nc1=O
InChI
InChI=1S/C27H52N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-35-20-16-21-37-38(33,34)24-36-25(23-31)22-30-18-17-26(28)29-27(30)32/h17-18,25,31H,2-16,19-24H2,1H3,(H,33,34)(H2,28,29,32)/t25-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C27H52N3O7P
Molecular Weight 561.7
AlogP 5.25
Hydrogen Bond Acceptor 9.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 26.0
Polar Surface Area 146.13
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 38.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR DNA polymerase inhibitor FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Smallpox 4 D012899 FDA
Cytomegalovirus Infections 3 D003586 ClinicalTrials
Adenoviridae Infections 3 D000257 ClinicalTrials
Hemorrhagic Fever, Ebola 2 D019142 ClinicalTrials
Adenovirus Infections, Human 2 D000258 ClinicalTrials
Virus Diseases 2 D014777 ClinicalTrials

Related Entries

MCS

Cross References

Resources Reference
CAS NUMBER 444805-28-1
ChEMBL CHEMBL203321
DrugBank DB12151
EPA CompTox DTXSID60196190
FDA SRS 6794O900AX
PubChem 483477
SureChEMBL SCHEMBL139922
ZINC ZINC000014141521
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