CADAZOLID

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 2OEA2UN10Y

Structure
InChI Key XWFCFMXQTBGXQW-GOSISDBHSA-N
Smile O=C(O)c1cn(C2CC2)c2cc(N3CCC(O)(COc4ccc(N5C[C@H](CO)OC5=O)cc4F)CC3)c(F)cc2c1=O
InChI
InChI=1S/C29H29F2N3O8/c30-21-10-19-23(33(16-1-2-16)13-20(26(19)36)27(37)38)11-24(21)32-7-5-29(40,6-8-32)15-41-25-4-3-17(9-22(25)31)34-12-18(14-35)42-28(34)39/h3-4,9-11,13,16,18,35,40H,1-2,5-8,12,14-15H2,(H,37,38)/t18-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C29H29F2N3O8
Molecular Weight 585.56
AlogP 3.04
Hydrogen Bond Acceptor 9.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 8.0
Polar Surface Area 141.77
Molecular species ACID
Aromatic Rings 3.0
Heavy Atoms 42.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Bacterial 70S ribosome inhibitor PubMed PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Clostridium Infections 3 D003015 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 1025097-10-2
ChEMBL CHEMBL3707376
DrugBank DB11847
EPA CompTox DTXSID10145234
FDA SRS 2OEA2UN10Y
Guide to Pharmacology 10767
PDB JJH
PubChem 44242317
SureChEMBL SCHEMBL541618
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