| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| ATC: | H03BB01 |
| UNII: | 8KQ660G60G |
Structure
| InChI Key | CFOYWRHIYXMDOT-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C7H10N2O2S |
| Molecular Weight | 186.24 |
| AlogP | 1.56 |
| Hydrogen Bond Acceptor | 5.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 1.0 |
| Polar Surface Area | 36.16 |
| Molecular species | None |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 12.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Oxidoreductase
|
- | 10400 | - | - | - | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 102 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Thyrotoxicosis | 3 | D013971 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 22232-54-8 |
| ChEBI | 617099 |
| ChEMBL | CHEMBL508102 |
| DrugBank | DB00389 |
| DrugCentral | 497 |
| EPA CompTox | DTXSID9022736 |
| FDA SRS | 8KQ660G60G |
| Human Metabolome Database | HMDB0014533 |
| KEGG | C07615 |
| PharmGKB | PA164742970 |
| PubChem | 31072 |
| SureChEMBL | SCHEMBL44211 |
| ZINC | ZINC000000001091 |
CONTENTS