CODEINE PHOSPHATE

Search structure
Synonyms:
Status: Approved (1952)
Entry Type: Small molecule
Molecule Category: Salt
UNII: GSL05Y1MN6
Parent Compound: CODEINE

Structure
InChI Key WUXLCJZUUHIXFY-FFHNEAJVSA-N
Smile COc1ccc2c3c1O[C@H]1[C@@H](O)C=C[C@H]4[C@@H](C2)N(C)CC[C@]314.O=P(O)(O)O
InChI
InChI=1S/C18H21NO3.H3O4P/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;1-5(2,3)4/h3-6,11-13,17,20H,7-9H2,1-2H3;(H3,1,2,3,4)/t11-,12+,13-,17-,18-;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H26NO8P
Molecular Weight 415.38
AlogP 1.5
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 1.0
Polar Surface Area 41.93
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 22.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Opioid receptors; mu/kappa/delta agonist
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) Short peptide receptor (family A GPCR) Opioid receptor
800000 10 - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
HIV Infections 3 D015658 ClinicalTrials
Sciatica 3 D012585 ClinicalTrials
Cough 1 D003371 ClinicalTrials

Related Entries

Scaffolds

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Cross References

Resources Reference
ChEMBL CHEMBL1201099
FDA SRS GSL05Y1MN6
PubChem 9953630
SureChEMBL SCHEMBL2515523
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