| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | Z5QU38B4V9 |
Structure
| InChI Key | ANDGGVOPIJEHOF-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C14H15N3O |
| Molecular Weight | 241.29 |
| AlogP | 2.26 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 1.0 |
| Polar Surface Area | 46.09 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 18.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Ion channel
Ligand-gated ion channel
Ionotropic glutamate receptor
AMPA receptor
|
95000 | - | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Cognitive Dysfunction | 2 | D060825 | ClinicalTrials |
| Schizophrenia | 2 | D012559 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 154235-83-3 |
| ChEBI | 34605 |
| ChEMBL | CHEMBL136800 |
| DrugBank | DB06247 |
| EPA CompTox | DTXSID70165574 |
| FDA SRS | Z5QU38B4V9 |
| Guide to Pharmacology | 4165 |
| KEGG | C13675 |
| PDB | CX5 |
| PubChem | 148184 |
| SureChEMBL | SCHEMBL194605 |
| ZINC | ZINC000000006489 |
CONTENTS