| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 2Z03364G96 |
Structure
| InChI Key | LQFRYKBDZNPJSW-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C4H7NO2S |
| Molecular Weight | 133.17 |
| AlogP | -0.06 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 57.93 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 8.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | NACHT, LRR and PYD domains-containing protein 3 inhibitor | PubMed |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Unclassified protein
|
- | 1 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Severe Acute Respiratory Syndrome | 2 | D045169 | ClinicalTrials |
| Schnitzler Syndrome | 2 | D019873 | ClinicalTrials |
| Heart Failure, Systolic | 1 | D054143 | ClinicalTrials |
| Melanoma | 1 | D008545 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3989943 |
| DrugBank | DB16130 |
| FDA SRS | 2Z03364G96 |
| Guide to Pharmacology | 10056 |
| PubChem | 12714644 |
| SureChEMBL | SCHEMBL9934796 |
| ZINC | ZINC000032005410 |
CONTENTS