DAPRODUSTAT

Search structure
Synonyms:
Status: Approved (2023)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: JVR38ZM64B

Structure
InChI Key RUEYEZADQJCKGV-UHFFFAOYSA-N
Smile O=C(O)CNC(=O)C1C(=O)N(C2CCCCC2)C(=O)N(C2CCCCC2)C1=O
InChI
InChI=1S/C19H27N3O6/c23-14(24)11-20-16(25)15-17(26)21(12-7-3-1-4-8-12)19(28)22(18(15)27)13-9-5-2-6-10-13/h12-13,15H,1-11H2,(H,20,25)(H,23,24)

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H27N3O6
Molecular Weight 393.44
AlogP 1.26
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 5.0
Polar Surface Area 124.09
Molecular species ACID
Aromatic Rings 0.0
Heavy Atoms 28.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Hypoxia-inducible factor prolyl hydroxylase inhibitor PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Anemia 3 D000740 ClinicalTrials
Peripheral Vascular Diseases 2 D016491 ClinicalTrials
Wounds and Injuries 1 D014947 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 960539-70-2
ChEMBL CHEMBL3544988
DrugBank DB11682
FDA SRS JVR38ZM64B
Guide to Pharmacology 8455
PubChem 91617630
ZINC ZINC000231226004
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