| Synonyms: | |
| Status: | Approved (1996) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| ATC: | N06DA02 |
| UNII: | 8SSC91326P |
Structure
| InChI Key | ADEBPBSSDYVVLD-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C24H29NO3 |
| Molecular Weight | 379.5 |
| AlogP | 4.36 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 38.77 |
| Molecular species | BASE |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 28.0 |
Pharmacology
| Primary Target | |
|---|---|
| acetylcholinesterase (Cartwright blood group) |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Anxiety | 3 | D001007 | ClinicalTrials |
| Multiple Sclerosis | 3 | D009103 | ClinicalTrials |
| Ischemic Stroke | 3 | D000083242 | ClinicalTrials |
| Depressive Disorder | 3 | D003866 | ClinicalTrials |
| Alzheimer Disease | 3 | D000544 | ClinicalTrials |
| Schizophrenia | 3 | D012559 | ClinicalTrials |
| Parkinson Disease | 3 | D010300 | ClinicalTrials |
| Cognitive Dysfunction | 3 | D060825 | ClinicalTrials |
| Neoplasms | 3 | D009369 | ClinicalTrials |
| Dementia, Vascular | 3 | D015140 | ClinicalTrials |
| Stroke | 3 | D020521 | ClinicalTrials |
| Aphasia | 3 | D001037 | ClinicalTrials |
| Diabetes Mellitus, Type 2 | 2 | D003924 | ClinicalTrials |
| Fragile X Syndrome | 2 | D005600 | ClinicalTrials |
| Tobacco Use Disorder | 2 | D014029 | ClinicalTrials |
| Neuralgia | 2 | D009437 | ClinicalTrials |
| Supranuclear Palsy, Progressive | 2 | D013494 | ClinicalTrials |
| Delirium | 2 | D003693 | ClinicalTrials |
| Wounds and Injuries | 2 | D014947 | ClinicalTrials |
| Cocaine-Related Disorders | 2 | D019970 | ClinicalTrials |
| Child Development Disorders, Pervasive | 2 | D002659 | ClinicalTrials |
| Amblyopia | 1 | D000550 | ClinicalTrials |
| Skin Diseases | 1 | D012871 | ClinicalTrials |
| Central Nervous System Diseases | 1 | D002493 | ClinicalTrials |
| Hearing Loss, Sensorineural | 1 | D006319 | ClinicalTrials |
| Urinary Retention | 1 | D016055 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 120014-06-4 |
| ChEBI | 53289 |
| ChEMBL | CHEMBL502 |
| DrugBank | DB00843 |
| DrugCentral | 946 |
| EPA CompTox | DTXSID8048317 |
| FDA SRS | 8SSC91326P |
| Human Metabolome Database | HMDB0005041 |
| Guide to Pharmacology | 6599 |
| PharmGKB | PA449394 |
| PubChem | 3152 |
| SureChEMBL | SCHEMBL2149 |
CONTENTS