DUTOGLIPTIN

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: Parent
UNII: 38EAO245ZX

Structure
InChI Key DVJAMEIQRSHVKC-BDAKNGLRSA-N
Smile O=C(CN[C@@H]1CCNC1)N1CCC[C@H]1B(O)O
InChI
InChI=1S/C10H20BN3O3/c15-10(7-13-8-3-4-12-6-8)14-5-1-2-9(14)11(16)17/h8-9,12-13,16-17H,1-7H2/t8-,9+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C10H20BN3O3
Molecular Weight 241.1
AlogP None
Hydrogen Bond Acceptor None
Hydrogen Bond Donor None
Number of Rotational Bond None
Polar Surface Area None
Molecular species None
Aromatic Rings None
Heavy Atoms None

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Dipeptidyl peptidase IV inhibitor PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Protease Serine protease Serine protease SC clan Serine protease S9B subfamily
- 23 - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetes Mellitus, Type 2 3 D003924 ClinicalTrials

Related Entries

UNKNOWN

Cross References

Resources Reference
CAS NUMBER 852329-66-9
ChEMBL CHEMBL4296719
DrugBank DB11723
FDA SRS 38EAO245ZX
PubChem 11253490
SureChEMBL SCHEMBL164106
ZINC ZINC000169746730
CONTENTS