| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| UNII: | 02DZ1HBF0M |
Structure
| InChI Key | WJIGGYYSZBWCGC-MRXNPFEDSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C16H25NO2 |
| Molecular Weight | 263.38 |
| AlogP | 3.03 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 55.48 |
| Molecular species | BASE |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 19.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Retinoid isomerohydrolase inhibitor | PubMed |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Stargardt Disease | 3 | D000080362 | ClinicalTrials |
| Macular Degeneration | 2 | D008268 | ClinicalTrials |
| Geographic Atrophy | 2 | D057092 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 1141777-14-1 |
| ChEMBL | CHEMBL2107821 |
| DrugBank | DB12608 |
| EPA CompTox | DTXSID50150665 |
| FDA SRS | 02DZ1HBF0M |
| PDB | A3V |
| PubChem | 25221720 |
| SureChEMBL | SCHEMBL966515 |
| ZINC | ZINC000059126886 |
CONTENTS