| Synonyms: | |
| Status: | Approved (2018) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| ATC: | J01AA13 |
| UNII: | 07896928ZC |
Structure
| InChI Key | HLFSMUUOKPBTSM-ISIOAQNYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C27H31FN4O8 |
| Molecular Weight | 558.56 |
| AlogP | 0.29 |
| Hydrogen Bond Acceptor | 10.0 |
| Hydrogen Bond Donor | 6.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 193.73 |
| Molecular species | ZWITTERION |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 40.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Other cytosolic protein
|
- | 620 | - | - | - | |
|
Unclassified protein
|
- | 620 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Infections | 3 | D007239 | ClinicalTrials |
| Urinary Tract Infections | 3 | D014552 | ClinicalTrials |
| Renal Insufficiency, Chronic | 1 | D051436 | ClinicalTrials |
| Liver Diseases | 1 | D008107 | ClinicalTrials |
Related Entries
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 1207283-85-9 |
| ChEMBL | CHEMBL1951095 |
| DrugBank | DB12329 |
| DrugCentral | 5294 |
| FDA SRS | 07896928ZC |
| Guide to Pharmacology | 10805 |
| SureChEMBL | SCHEMBL10040430 |
CONTENTS