| Synonyms: | |
| Status: | Approved (2012) |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 6867Q6IKOD |
Structure
| InChI Key | YNDIAUKFXKEXSV-NSCUHMNNSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C20H25FN2O3 |
| Molecular Weight | 360.43 |
| AlogP | 3.68 |
| Hydrogen Bond Acceptor | 5.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 12.0 |
| Polar Surface Area | 52.61 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 26.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
|
- | - | - | 11-13 | - |
Indications
| Mesh Heading | Maximum Phase | Reference |
|---|---|---|
| Cognition Disorders; Dementia | Phase 3 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL1908919 |
| EPA CompTox | DTXSID90239781 |
| FDA SRS | 6867Q6IKOD |
| Guide to Pharmacology | 7344 |
| PubChem | 57396865 |
| SureChEMBL | SCHEMBL3356976 |
| ZINC | ZINC000043207237 |
CONTENTS