FLUDROCORTISONE

Search structure
Status: Approved
Entry Type: Unknown
Molecule Category: Parent
ATC: H02AA02

Structure
InChI Key AAXVEMMRQDVLJB-BULBTXNYSA-N
Smile C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO
InChI
InChI=1S/C21H29FO5/c1-18-7-5-13(24)9-12(18)3-4-15-14-6-8-20(27,17(26)11-23)19(14,2)10-16(25)21(15,18)22/h9,14-16,23,25,27H,3-8,10-11H2,1-2H3/t14-,15-,16-,18-,19-,20-,21-/m0/s1

Pharmacology

Primary Target
Mineralocorticoid receptor

Indications

Mesh Heading Maximum Phase Reference
Depression Phase 1 ClinicalTrials
Hypersensitivity; Hypertension Phase 4 ClinicalTrials
Shock; Shock, Septic Phase 3 ClinicalTrials
Shock; Shock, Septic Phase 3 ClinicalTrials
Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adrenogenital Syndrome; Hyperplasia Phase 2 ClinicalTrials
Atrophy; Hypotension; Hypotension, Orthostatic; Multiple System Atrophy; Parkinson Disease; Shy-Drager Syndrome Phase 1 ClinicalTrials
Parkinson Disease Phase 2 ClinicalTrials

Related Entries

MCS

Scaffolds

Salt
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