LINZAGOLIX

Search structure
Synonyms:
Status: Phase 1
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 7CDW97HUEX

Structure
InChI Key BMAAMIIYNNPHAB-UHFFFAOYSA-N
Smile COc1cc(F)c(-n2c(=O)[nH]c3csc(C(=O)O)c3c2=O)cc1OCc1c(OC)ccc(F)c1F
InChI
InChI=1S/C22H15F3N2O7S/c1-32-14-4-3-10(23)18(25)9(14)7-34-16-6-13(11(24)5-15(16)33-2)27-20(28)17-12(26-22(27)31)8-35-19(17)21(29)30/h3-6,8H,7H2,1-2H3,(H,26,31)(H,29,30)

Physicochemical Descriptors

Property Name Value
Molecular Formula C22H15F3N2O7S
Molecular Weight 508.43
AlogP 3.45
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 7.0
Polar Surface Area 119.85
Molecular species ACID
Aromatic Rings 4.0
Heavy Atoms 35.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Gonadotropin-releasing hormone receptor antagonist Other

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Endometriosis 3 D004715 ClinicalTrials
Liver Diseases 1 D008107 ClinicalTrials
Kidney Diseases 1 D007674 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL3668014
FDA SRS 7CDW97HUEX
PubChem 16656889
SureChEMBL SCHEMBL2333748
ZINC ZINC000043152963
CONTENTS