LONIDAMINE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: L01XX07
UNII: U78804BIDR

Structure
InChI Key WDRYRZXSPDWGEB-UHFFFAOYSA-N
Smile O=C(O)c1nn(Cc2ccc(Cl)cc2Cl)c2ccccc12
InChI
InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)

Physicochemical Descriptors

Property Name Value
Molecular Formula C15H10Cl2N2O2
Molecular Weight 321.16
AlogP 4.09
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 3.0
Polar Surface Area 55.12
Molecular species ACID
Aromatic Rings 3.0
Heavy Atoms 21.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 108

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Prostatic Hyperplasia 3 D011470 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 50264-69-2
ChEBI 50138
ChEMBL CHEMBL1257030
DrugBank DB06266
DrugCentral 1598
EPA CompTox DTXSID5020782
FDA SRS U78804BIDR
PubChem 39562
SureChEMBL SCHEMBL7134
ZINC ZINC000000001632
CONTENTS