MOTESANIB DIPHOSPHATE

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: Salt
UNII: T6Q3060U91
Parent Compound: MOTESANIB

Structure
InChI Key ONDPWWDPQDCQNJ-UHFFFAOYSA-N
Smile CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc21.O=P(O)(O)O.O=P(O)(O)O
InChI
InChI=1S/C22H23N5O.2H3O4P/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15;2*1-5(2,3)4/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28);2*(H3,1,2,3,4)

Physicochemical Descriptors

Property Name Value
Molecular Formula C22H29N5O9P2
Molecular Weight 569.45
AlogP 4.04
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 5.0
Polar Surface Area 78.94
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 28.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Carcinoma, Non-Small-Cell Lung 3 D002289 ClinicalTrials
Gastrointestinal Stromal Tumors 2 D046152 ClinicalTrials
Neoplasms 2 D009369 ClinicalTrials
Carcinoid Tumor 2 D002276 ClinicalTrials
Adenoma, Islet Cell 2 D007516 ClinicalTrials
Peritoneal Neoplasms 2 D010534 ClinicalTrials
Thyroid Neoplasms 2 D013964 ClinicalTrials
Fallopian Tube Neoplasms 2 D005185 ClinicalTrials
Breast Neoplasms 2 D001943 ClinicalTrials
Ovarian Neoplasms 2 D010051 ClinicalTrials
Pancreatic Neoplasms 1 D010190 ClinicalTrials
Lymphoma 1 D008223 ClinicalTrials
Lung Neoplasms 1 D008175 ClinicalTrials
Colonic Neoplasms 1 D003110 ClinicalTrials
Rectal Neoplasms 1 D012004 ClinicalTrials
Esophageal Neoplasms 1 D004938 ClinicalTrials
Lymphoproliferative Disorders 1 D008232 ClinicalTrials

Related Entries

Parent

Cross References

Resources Reference
ChEMBL CHEMBL2107357
EPA CompTox DTXSID30235080
FDA SRS T6Q3060U91
PubChem 16097729
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