| Synonyms: | |
| Status: | Approved |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 8UQ3W6JXAN |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C2H8N2O3Pt |
| Molecular Weight | 303.18 |
| AlogP | None |
| Hydrogen Bond Acceptor | None |
| Hydrogen Bond Donor | None |
| Number of Rotational Bond | None |
| Polar Surface Area | None |
| Molecular species | None |
| Aromatic Rings | None |
| Heavy Atoms | None |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Transferase
|
- | - | - | - | 0.8107 | |
|
Epigenetic regulator
Eraser
Histone deacetylase
HDAC class IIb
|
- | - | - | - | -26.62--1.32 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Nasopharyngeal Carcinoma | 3 | D000077274 | ClinicalTrials |
| Carcinoma, Non-Small-Cell Lung | 3 | D002289 | ClinicalTrials |
| Esophageal Neoplasms | 3 | D004938 | ClinicalTrials |
| Carcinoma, Squamous Cell | 3 | D002294 | ClinicalTrials |
| Carcinoma, Squamous Cell | 3 | D002294 | ClinicalTrials |
| Esophageal Neoplasms | 3 | D004938 | ClinicalTrials |
| Esophageal Neoplasms | 3 | D004938 | ClinicalTrials |
| Central Nervous System Neoplasms | 2 | D016543 | ClinicalTrials |
| Uterine Cervical Neoplasms | 2 | D002583 | ClinicalTrials |
| Hypopharyngeal Neoplasms | 2 | D007012 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 95734-82-0 |
| ChEMBL | CHEMBL3137685 |
| FDA SRS | 8UQ3W6JXAN |
| PubChem | 9796440 |
CONTENTS