| Synonyms: | |
| Status: | Approved (1971) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| ATC: | J01CF04 |
| UNII: | UH95VD7V76 |
Structure
| InChI Key | UWYHMGVUTGAWSP-JKIFEVAISA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C19H19N3O5S |
| Molecular Weight | 401.44 |
| AlogP | 1.9 |
| Hydrogen Bond Acceptor | 6.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 4.0 |
| Polar Surface Area | 112.74 |
| Molecular species | ACID |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 28.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Transferase
|
- | - | - | - | 5 | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC22 family of organic cation and anion transporters
|
- | 35000 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Bacteremia | 3 | D016470 | ClinicalTrials |
| Osteomyelitis | 3 | D010019 | ClinicalTrials |
| Gram-Positive Bacterial Infections | 3 | D016908 | ClinicalTrials |
| Infections | 2 | D007239 | ClinicalTrials |
Related Entries
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 66-79-5 |
| ChEBI | 7809 |
| ChEMBL | CHEMBL819 |
| DrugBank | DB00713 |
| DrugCentral | 2006 |
| EPA CompTox | DTXSID8023397 |
| FDA SRS | UH95VD7V76 |
| Human Metabolome Database | HMDB0014851 |
| Guide to Pharmacology | 10943 |
| KEGG | C07334 |
| PharmGKB | PA450725 |
| PubChem | 6196 |
| SureChEMBL | SCHEMBL3817 |
| ZINC | ZINC000003875439 |
CONTENTS