| Synonyms: | |
| Status: | Approved (1967) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| ATC: | N02AD01 |
| UNII: | RP4A60D26L |
Structure
| InChI Key | VOKSWYLNZZRQPF-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C19H27NO |
| Molecular Weight | 285.43 |
| AlogP | 3.88 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 23.47 |
| Molecular species | BASE |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 21.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
Family A G protein-coupled receptor
Peptide receptor (family A GPCR)
Short peptide receptor (family A GPCR)
Opioid receptor
|
61-61 | 280-280 | - | 2.7-3.9 | - | |
|
Membrane receptor
|
61-61 | 280-280 | - | 2.7-3.9 | - | |
|
Other membrane protein
|
- | - | 2.9 | 3.1-15 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Bipolar Disorder | 2 | D001714 | ClinicalTrials |
Related Entries
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 359-83-1 |
| ChEBI | 182080 |
| ChEMBL | CHEMBL100116 |
| DrugBank | DB00652 |
| DrugCentral | 3424 |
| FDA SRS | RP4A60D26L |
| PubChem | 4736 |
| SureChEMBL | SCHEMBL2493 |
CONTENTS