PHENTERMINE

Search structure
Synonyms:
Status: Approved (1959)
Entry Type: Small molecule
Molecule Category: Parent
ATC: A08AA01
UNII: C045TQL4WP

Structure
InChI Key DHHVAGZRUROJKS-UHFFFAOYSA-N
Smile CC(C)(N)Cc1ccccc1
InChI
InChI=1S/C10H15N/c1-10(2,11)8-9-6-4-3-5-7-9/h3-7H,8,11H2,1-2H3

Physicochemical Descriptors

Property Name Value
Molecular Formula C10H15N
Molecular Weight 149.24
AlogP 1.97
Hydrogen Bond Acceptor 1.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 2.0
Polar Surface Area 26.02
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 11.0

Pharmacology

Action Mechanism of Action Reference
RELEASING AGENT Norepinephrine transporter releasing agent PubMed Wikipedia
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Oxidoreductase
- - - - 0
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Trace amine receptor
5470 - - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetes Mellitus 2 D003920 ClinicalTrials
Obesity, Morbid 2 D009767 ClinicalTrials
Kidney Diseases 1 D007674 ClinicalTrials
Liver Diseases 1 D008107 ClinicalTrials
Substance-Related Disorders 1 D019966 ClinicalTrials
Bulimia Nervosa 1 D052018 ClinicalTrials

Related Entries

Salt

Cross References

Resources Reference
CAS NUMBER 122-09-8
ChEBI 8080
ChEMBL CHEMBL1574
DrugBank DB00191
DrugCentral 2140
EPA CompTox DTXSID9023461
FDA SRS C045TQL4WP
Human Metabolome Database HMDB0014337
Guide to Pharmacology 7269
KEGG C07438
PharmGKB PA164748099
PubChem 4771
SureChEMBL SCHEMBL26615
ZINC ZINC000008403947
CONTENTS