RAPASTINEL

Search structure
Synonyms:
Status: Phase 3
Entry Type: Protein
Molecule Category: UNKNOWN
UNII: 6A1X56B95E

Structure
InChI Key GIBQQARAXHVEGD-BSOLPCOYSA-N
Smile C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)[C@@H](C)O
InChI
InChI=1S/C18H31N5O6/c1-9(24)13(19)18(29)23-8-4-6-12(23)17(28)22-7-3-5-11(22)16(27)21-14(10(2)25)15(20)26/h9-14,24-25H,3-8,19H2,1-2H3,(H2,20,26)(H,21,27)/t9-,10-,11+,12+,13+,14+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H31N5O6
Molecular Weight 413.48
AlogP -2.97
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 7.0
Polar Surface Area 179.29
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 29.0

Pharmacology

Action Mechanism of Action Reference
PARTIAL AGONIST Glutamate [NMDA] receptor partial agonist PubMed PubMed Wikipedia

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Depressive Disorder, Major 3 D003865 ClinicalTrials
Obsessive-Compulsive Disorder 2 D009771 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 117928-94-6
ChEMBL CHEMBL3544917
DrugBank DB11801
FDA SRS 6A1X56B95E
PubChem 14539800
SureChEMBL SCHEMBL1668190
ZINC ZINC000071773625
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