RELAMORELIN

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: BIW199E18V

Structure
InChI Key KUBPNVYPKPWGRJ-LIVOIKKVSA-N
Smile NC(=O)C1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2csc3ccccc23)NC(=O)C2CCNCC2)CCNCC1
InChI
InChI=1S/C43H50N8O5S/c44-42(56)43(16-20-46-21-17-43)51-41(55)34(22-27-8-2-1-3-9-27)49-39(53)35(23-29-25-47-33-12-6-4-10-31(29)33)50-40(54)36(48-38(52)28-14-18-45-19-15-28)24-30-26-57-37-13-7-5-11-32(30)37/h1-13,25-26,28,34-36,45-47H,14-24H2,(H2,44,56)(H,48,52)(H,49,53)(H,50,54)(H,51,55)/t34-,35+,36+/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C43H50N8O5S
Molecular Weight 790.99
AlogP 2.59
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 8.0
Number of Rotational Bond 15.0
Polar Surface Area 199.34
Molecular species BASE
Aromatic Rings 5.0
Heavy Atoms 57.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Ghrelin receptor agonist PubMed PubMed PubMed

Indications

Mesh Heading Maximum Phase Reference
Gastroparesis Phase 3 ClinicalTrials
Diabetes Complications; Diabetes Mellitus; Gastroparesis; Vomiting Phase 2 ClinicalTrials
Gastroparesis Phase 3 ClinicalTrials
Gastroparesis Phase 3 ClinicalTrials
Gastroparesis Phase 3 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 661472-41-9
ChEMBL CHEMBL4297525
DrugBank DB12678
FDA SRS BIW199E18V
PubChem 85364156
SureChEMBL SCHEMBL19606783
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