| Synonyms: | |
| Status: | Approved (2018) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| ATC: | P01BA07 |
| UNII: | 262P8GS9L9 |
Structure
| InChI Key | LBHLFPGPEGDCJG-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value | |
|---|---|---|
| Molecular Formula | C24H28F3N3O3 | |
| Molecular Weight | 463.5 | |
| AlogP | 5.91 | |
| Hydrogen Bond Acceptor | 6.0 | |
| Hydrogen Bond Donor | 2.0 | |
| Number of Rotational Bond | 9.0 | |
| Polar Surface Area | 78.63 | |
| Molecular species | BASE | |
| Aromatic Rings | 3.0 | |
| Heavy Atoms | 33.0 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference | ||
|---|---|---|---|---|---|
| Malaria | 4 | D008288 | ClinicalTrials | ||
| Malaria, Vivax | 3 | D016780 | ClinicalTrials | ||
| Malaria, Falciparum | 2 | D016778 | ClinicalTrials | ||
| Severe Acute Respiratory Syndrome | 2 | D045169 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 106635-80-7 |
| ChEBI | 141487 |
| ChEMBL | CHEMBL298470 |
| DrugBank | DB06608 |
| DrugCentral | 3578 |
| FDA SRS | 262P8GS9L9 |
| Guide to Pharmacology | 9722 |
| PharmGKB | PA166115580 |
| PubChem | 115358 |
| SureChEMBL | SCHEMBL347388 |
CONTENTS