TALABOSTAT

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: Parent
UNII: KZ1O2SH88Z

Structure
InChI Key PHCFSFBQEROREL-BQBZGAKWSA-N
Smile CC[C@H](N)C(=O)N1CCC[C@H]1B(O)O
InChI
InChI=1S/C8H17BN2O3/c1-2-6(10)8(12)11-5-3-4-7(11)9(13)14/h6-7,13-14H,2-5,10H2,1H3/t6-,7-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C9H19BN2O3
Molecular Weight 214.07
AlogP None
Hydrogen Bond Acceptor None
Hydrogen Bond Donor None
Number of Rotational Bond None
Polar Surface Area None
Molecular species None
Aromatic Rings None
Heavy Atoms None

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Protease Serine protease Serine protease SC clan Serine protease S28 family
- 15-86 - 125-125 -
Enzyme Protease Serine protease Serine protease SC clan Serine protease S9A subfamily
- 73-23000 - - -
Enzyme Protease Serine protease Serine protease SC clan Serine protease S9B subfamily
- 0-1200 - 0-2000 -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Carcinoma, Non-Small-Cell Lung 3 D002289 ClinicalTrials
Neoplasms 2 D009369 ClinicalTrials
Skin Neoplasms 2 D012878 ClinicalTrials
Melanoma 2 D008545 ClinicalTrials
Kidney Neoplasms 2 D007680 ClinicalTrials
Lung Neoplasms 2 D008175 ClinicalTrials
Pancreatic Neoplasms 0 D010190 ClinicalTrials

Related Entries

Salt

Cross References

Resources Reference
CAS NUMBER 149682-77-9
ChEMBL CHEMBL67279
DrugBank DB06182
FDA SRS KZ1O2SH88Z
Guide to Pharmacology 9892
PubChem 6918572
SureChEMBL SCHEMBL393024
ZINC ZINC000169746694
CONTENTS