Pharmacology

Action Mechanism of Action Reference
INHIBITOR Cytotoxic T-lymphocyte protein 4 inhibitor PubMed PubMed
Primary Target
cytotoxic T-lymphocyte-associated protein 4 (CD152)

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Melanoma 3 D008545 ClinicalTrials
Urinary Bladder Neoplasms 3 D001749 ClinicalTrials
Melanoma 3 D008545 ClinicalTrials
Neoplasms 3 D009369 ClinicalTrials
Carcinoma, Renal Cell 3 D002292 ClinicalTrials
Carcinoma, Non-Small-Cell Lung 3 D002289 ClinicalTrials
Small Cell Lung Carcinoma 3 D055752 ClinicalTrials
Carcinoma, Squamous Cell 3 D002294 ClinicalTrials
Carcinoma, Squamous Cell 3 D002294 ClinicalTrials
Melanoma 3 D008545 ClinicalTrials
Urogenital Neoplasms 3 D014565 ClinicalTrials
Carcinoma, Hepatocellular 3 D006528 ClinicalTrials
Urinary Bladder Neoplasms 3 D001749 ClinicalTrials
Neoplasms 3 D009369 ClinicalTrials
Genital Neoplasms, Female 2 D005833 ClinicalTrials
Mesothelioma 2 D008654 ClinicalTrials
Breast Neoplasms 2 D001943 ClinicalTrials
Pancreatic Neoplasms 2 D010190 ClinicalTrials
Glioblastoma 2 D005909 ClinicalTrials
Stomach Neoplasms 2 D013274 ClinicalTrials
Neoplasms, Germ Cell and Embryonal 2 D009373 ClinicalTrials
Prostatic Neoplasms 2 D011471 ClinicalTrials
Sarcoma 2 D012509 ClinicalTrials
HIV Infections 2 D015658 ClinicalTrials
Ovarian Neoplasms 2 D010051 ClinicalTrials
Carcinoma, Pancreatic Ductal 2 D021441 ClinicalTrials
Seminoma 2 D018239 ClinicalTrials
Dysgerminoma 2 D004407 ClinicalTrials
Breast Neoplasms 2 D001943 ClinicalTrials
Ovarian Neoplasms 2 D010051 ClinicalTrials
Prostatic Neoplasms, Castration-Resistant 2 D064129 ClinicalTrials
Lung Neoplasms 2 D008175 ClinicalTrials
Squamous Cell Carcinoma of Head and Neck 2 D000077195 ClinicalTrials
Squamous Cell Carcinoma of Head and Neck 2 D000077195 ClinicalTrials
Biliary Tract Neoplasms 2 D001661 ClinicalTrials
Colorectal Neoplasms 2 D015179 ClinicalTrials
Head and Neck Neoplasms 2 D006258 ClinicalTrials
Colorectal Neoplasms 2 D015179 ClinicalTrials
Carcinoma 2 D002277 ClinicalTrials
Adenocarcinoma, Follicular 2 D018263 ClinicalTrials
Thyroid Neoplasms 2 D013964 ClinicalTrials
Fallopian Tube Neoplasms 2 D005185 ClinicalTrials
Colorectal Neoplasms 2 D015179 ClinicalTrials
Neuroendocrine Tumors 2 D018358 ClinicalTrials
Cholangiocarcinoma 2 D018281 ClinicalTrials
Cholangiocarcinoma 2 D018281 ClinicalTrials
Sarcoma 2 D012509 ClinicalTrials
Stomach Neoplasms 2 D013274 ClinicalTrials
Thyroid Neoplasms 2 D013964 ClinicalTrials
Fallopian Tube Neoplasms 2 D005185 ClinicalTrials
Myelodysplastic Syndromes 1 D009190 ClinicalTrials
Hematologic Neoplasms 1 D019337 ClinicalTrials
Lymphoma, Large B-Cell, Diffuse 1 D016403 ClinicalTrials
Lymphoma 1 D008223 ClinicalTrials
Peritoneal Neoplasms 1 D010534 ClinicalTrials
Esophageal Neoplasms 1 D004938 ClinicalTrials
Multiple Myeloma 1 D009101 ClinicalTrials
Kidney Neoplasms 0 D007680 ClinicalTrials

Cross References

Resources Reference
CAS NUMBER 745013-59-6
ChEMBL CHEMBL2108658
FDA SRS QEN1X95CIX
Guide to Pharmacology 8462