VOGLIBOSE

Search structure
Synonyms:
Status: Approved
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: A10BF03
UNII: S77P977AG8

Structure
InChI Key FZNCGRZWXLXZSZ-CIQUZCHMSA-N
Smile OCC(CO)N[C@H]1C[C@](O)(CO)[C@@H](O)[C@H](O)[C@H]1O
InChI
InChI=1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2/t6-,7-,8+,9-,10-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C10H21NO7
Molecular Weight 267.28
AlogP -4.49
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 8.0
Number of Rotational Bond 5.0
Polar Surface Area 153.64
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 18.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Alpha glucosidase inhibitor PubMed PubMed PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- 110-1200 - - -
Enzyme
- 70-5200 - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetes Mellitus, Type 2 3 D003924 ClinicalTrials

Cross References

Resources Reference
CAS NUMBER 83480-29-9
ChEBI 32300
ChEMBL CHEMBL476960
DrugBank DB04878
DrugCentral 2845
EPA CompTox DTXSID2021442
FDA SRS S77P977AG8
Human Metabolome Database HMDB0015598
PDB VOG
PharmGKB PA164752433
PubChem 444020
SureChEMBL SCHEMBL5882
ZINC ZINC000003788703
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