| Synonyms: | |
| Status: | Approved (1985) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| UNII: | H4N855PNZ1 |
Structure
| InChI Key | GVJHHUAWPYXKBD-IEOSBIPESA-N |
|---|---|
| Smile | |
| InChI |
|
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Oxidoreductase
|
1.48 | - | - | - | 3.9 | |
|
Enzyme
Transferase
|
- | - | - | - | 16.12-23.31 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Fatty Liver | 3 | D005234 | ClinicalTrials |
| Liver Diseases | 3 | D008107 | ClinicalTrials |
| Macular Degeneration | 3 | D008268 | ClinicalTrials |
| Urinary Bladder Neoplasms | 3 | D001749 | ClinicalTrials |
| Breast Neoplasms | 3 | D001943 | ClinicalTrials |
| Glaucoma | 3 | D005901 | ClinicalTrials |
| Prostatic Neoplasms, Castration-Resistant | 3 | D064129 | ClinicalTrials |
| Pain | 3 | D010146 | ClinicalTrials |
| Osteonecrosis | 3 | D010020 | ClinicalTrials |
| Rectal Neoplasms | 3 | D012004 | ClinicalTrials |
| Non-alcoholic Fatty Liver Disease | 3 | D065626 | ClinicalTrials |
| Depressive Disorder | 3 | D003866 | ClinicalTrials |
| Vascular Diseases | 3 | D014652 | ClinicalTrials |
| Alzheimer Disease | 3 | D000544 | ClinicalTrials |
| Amyotrophic Lateral Sclerosis | 3 | D000690 | ClinicalTrials |
| Psoriasis | 3 | D011565 | ClinicalTrials |
| Schizophrenia | 3 | D012559 | ClinicalTrials |
| Cataract | 3 | D002386 | ClinicalTrials |
| Breast Neoplasms | 3 | D001943 | ClinicalTrials |
| Parkinson Disease | 3 | D010300 | ClinicalTrials |
| Migraine Disorders | 3 | D008881 | ClinicalTrials |
| Liver Cirrhosis | 3 | D008103 | ClinicalTrials |
| Hypobetalipoproteinemias | 3 | D006995 | ClinicalTrials |
| Retinitis Pigmentosa | 3 | D012174 | ClinicalTrials |
| Menopause | 3 | D008593 | ClinicalTrials |
| Osteonecrosis | 3 | D010020 | ClinicalTrials |
| Coronary Disease | 3 | D003327 | ClinicalTrials |
| Head and Neck Neoplasms | 3 | D006258 | ClinicalTrials |
| Pulmonary Disease, Chronic Obstructive | 3 | D029424 | ClinicalTrials |
| Head and Neck Neoplasms | 3 | D006258 | ClinicalTrials |
| Kidney Diseases | 3 | D007674 | ClinicalTrials |
| Delirium | 3 | D003693 | ClinicalTrials |
| Non-alcoholic Fatty Liver Disease | 3 | D065626 | ClinicalTrials |
| Myocardial Infarction | 3 | D009203 | ClinicalTrials |
| Infections | 3 | D007239 | ClinicalTrials |
| Myocardial Ischemia | 3 | D017202 | ClinicalTrials |
| Cerebrovascular Disorders | 3 | D002561 | ClinicalTrials |
| Colorectal Neoplasms | 3 | D015179 | ClinicalTrials |
| Gaucher Disease | 3 | D005776 | ClinicalTrials |
| Lung Neoplasms | 2 | D008175 | ClinicalTrials |
| Wounds and Injuries | 2 | D014947 | ClinicalTrials |
| Polycystic Ovary Syndrome | 2 | D011085 | ClinicalTrials |
| Endometriosis | 2 | D004715 | ClinicalTrials |
| Reperfusion Injury | 2 | D015427 | ClinicalTrials |
| Peripheral Nervous System Diseases | 2 | D010523 | ClinicalTrials |
| Heart Failure | 2 | D006333 | ClinicalTrials |
| Tobacco Use Disorder | 2 | D014029 | ClinicalTrials |
| Heart Diseases | 2 | D006331 | ClinicalTrials |
| Carotid Artery Diseases | 2 | D002340 | ClinicalTrials |
| Renal Insufficiency, Chronic | 2 | D051436 | ClinicalTrials |
| Atherosclerosis | 2 | D050197 | ClinicalTrials |
| Brain Diseases | 2 | D001927 | ClinicalTrials |
| Fibrosis | 2 | D005355 | ClinicalTrials |
| Burns | 2 | D002056 | ClinicalTrials |
| Intracranial Arteriosclerosis | 2 | D002537 | ClinicalTrials |
| Mastodynia | 2 | D059373 | ClinicalTrials |
| Heavy Metal Poisoning | 2 | D000075322 | ClinicalTrials |
| Neuromuscular Diseases | 2 | D009468 | ClinicalTrials |
| Stomatitis | 2 | D013280 | ClinicalTrials |
| Acute Kidney Injury | 2 | D058186 | ClinicalTrials |
| Cardiovascular Diseases | 2 | D002318 | ClinicalTrials |
| Infertility, Male | 2 | D007248 | ClinicalTrials |
| Diabetes Mellitus, Type 2 | 2 | D003924 | ClinicalTrials |
| Adrenoleukodystrophy | 2 | D000326 | ClinicalTrials |
| Friedreich Ataxia | 2 | D005621 | ClinicalTrials |
| Neoplasms | 2 | D009369 | ClinicalTrials |
| Asthenozoospermia | 2 | D053627 | ClinicalTrials |
| Ovarian Neoplasms | 1 | D010051 | ClinicalTrials |
| Anemia | 1 | D000740 | ClinicalTrials |
| Pancreatic Neoplasms | 1 | D010190 | ClinicalTrials |
| Pancreatic Neoplasms | 1 | D010190 | ClinicalTrials |
| Infertility | 1 | D007246 | ClinicalTrials |
| Arthritis, Rheumatoid | 1 | D001172 | ClinicalTrials |
| Asthma | 1 | D001249 | ClinicalTrials |
| Penile Induration | 1 | D010411 | ClinicalTrials |
Related Entries
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 59-02-9 |
| ChEMBL | CHEMBL3989727 |
| FDA SRS | H4N855PNZ1 |
CONTENTS