CILAZAPRIL

Search structure
Synonyms:
Status: Approved
Entry Type: Small molecule
Molecule Category: Parent
ATC: C09AA08
UNII: 8Q9454114Q

Structure
InChI Key HHHKFGXWKKUNCY-FHWLQOOXSA-N
Smile CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CCCN2CCC[C@@H](C(=O)O)N2C1=O
InChI
InChI=1S/C22H31N3O5/c1-2-30-22(29)18(13-12-16-8-4-3-5-9-16)23-17-10-6-14-24-15-7-11-19(21(27)28)25(24)20(17)26/h3-5,8-9,17-19,23H,2,6-7,10-15H2,1H3,(H,27,28)/t17-,18-,19-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C22H31N3O5
Molecular Weight 417.51
AlogP 1.6
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 8.0
Polar Surface Area 99.18
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 30.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Angiotensin-converting enzyme inhibitor PubMed PubMed PubMed PubMed PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 3698
ChEMBL CHEMBL515606
DrugBank DB01340
DrugCentral 641
EPA CompTox DTXSID1048629
FDA SRS 8Q9454114Q
Human Metabolome Database HMDB0015433
Guide to Pharmacology 6459
SureChEMBL SCHEMBL24962
ZINC ZINC000003781951
CONTENTS