| Synonyms: | |
| Status: | Approved (1994) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| ATC: | D04AA16 |
| UNII: | 134FM9ZZ6M |
Structure
| InChI Key | IJHNSHDBIRRJRN-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C16H20N2 |
| Molecular Weight | 240.35 |
| AlogP | 3.17 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 16.13 |
| Molecular species | BASE |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 18.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Ion channel
Voltage-gated ion channel
Voltage-gated sodium channel
|
- | 33000 | - | - | 25 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Common Cold | 3 | D003139 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 91591 |
| ChEMBL | CHEMBL1193 |
| DrugBank | DB01620 |
| DrugCentral | 2132 |
| EPA CompTox | DTXSID0023454 |
| FDA SRS | 134FM9ZZ6M |
| Human Metabolome Database | HMDB0015557 |
| Guide to Pharmacology | 7267 |
| PharmGKB | PA164744506 |
| PubChem | 4761 |
| SureChEMBL | SCHEMBL4796 |
CONTENTS