LODOXAMIDE

Search structure
Synonyms:
Status: Approved (1993)
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: S01GX05
UNII: SPU695OD73

Structure
InChI Key RVGLGHVJXCETIO-UHFFFAOYSA-N
Smile N#Cc1cc(NC(=O)C(=O)O)c(Cl)c(NC(=O)C(=O)O)c1
InChI
InChI=1S/C11H6ClN3O6/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21)

Physicochemical Descriptors

Property Name Value
Molecular Formula C11H6ClN3O6
Molecular Weight 311.64
AlogP 0.26
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 2.0
Polar Surface Area 156.59
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 21.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Carboxylic acid receptor Kynurenic acid receptor
4000 - - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Cross References

Resources Reference
ChEBI 135333
ChEMBL CHEMBL1201266
DrugBank DB06794
DrugCentral 3325
EPA CompTox DTXSID9057767
FDA SRS SPU695OD73
Guide to Pharmacology 9743
PubChem 44564
SureChEMBL SCHEMBL119881
ZINC ZINC000002000707
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