| Synonyms: | |
| Status: | Approved (1986) |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | K848JZ4886 |
Structure
| InChI Key | XUJNEKJLAYXESH-REOHCLBHSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C3H7NO2S |
| Molecular Weight | 121.16 |
| AlogP | -0.67 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 63.32 |
| Molecular species | ZWITTERION |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 7.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC03 and SLC07 families of heteromeric amino acid transporters (HATs)
SLC07 Cationic amino acid transporter/glycoprotein-associated family
|
- | - | - | 59000 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Uremia | 2 | D014511 | ClinicalTrials |
| Vitamin D Deficiency | 0 | D014808 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 17561 |
| ChEMBL | CHEMBL863 |
| DrugBank | DB00151 |
| DrugCentral | 769 |
| EPA CompTox | DTXSID8022876 |
| FDA SRS | K848JZ4886 |
| Human Metabolome Database | HMDB0000574 |
| Guide to Pharmacology | 4782 |
| KEGG | C00097 |
| PDB | CYS |
| PharmGKB | PA449173 |
| PubChem | 5862 |
| SureChEMBL | SCHEMBL3349 |
| ZINC | ZINC000000895042 |
CONTENTS