| Synonyms: | |
| Status: | Phase 1 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 4N173XZ7SX |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C18H19N5O |
| Molecular Weight | 321.38 |
| AlogP | 2.85 |
| Hydrogen Bond Acceptor | 5.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 3.0 |
| Polar Surface Area | 77.83 |
| Molecular species | None |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 24.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Serine/threonine-protein kinase Chk1 inhibitor |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Neoplasms | 1 | D009369 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3545007 |
| FDA SRS | 4N173XZ7SX |
CONTENTS