CO-TRIMOXAZOLE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN

Structure
InChI Key WZRJTRPJURQBRM-UHFFFAOYSA-N
Smile COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC.Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI
InChI=1S/C14H18N4O3.C10H11N3O3S/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2-6H,11H2,1H3,(H,12,13)

Physicochemical Descriptors

Property Name Value
Molecular Formula C25H30N6O6S
Molecular Weight 542.62
AlogP None
Hydrogen Bond Acceptor None
Hydrogen Bond Donor None
Number of Rotational Bond None
Polar Surface Area None
Molecular species None
Aromatic Rings None
Heavy Atoms None

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Bacterial dihydrofolate reductase inhibitor Other FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Bacterial Infections 3 D001424 ClinicalTrials
Sepsis 3 D018805 ClinicalTrials
Tuberculosis 2 D014376 ClinicalTrials
Severe Acute Respiratory Syndrome 2 D045169 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL195591
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