AMENAMEVIR

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: J05AX26
UNII: 94X46KW4AE

Structure
InChI Key MNHNIVNAFBSLLX-UHFFFAOYSA-N
Smile Cc1cccc(C)c1N(CC(=O)Nc1ccc(-c2ncon2)cc1)C(=O)C1CCS(=O)(=O)CC1
InChI
InChI=1S/C24H26N4O5S/c1-16-4-3-5-17(2)22(16)28(24(30)19-10-12-34(31,32)13-11-19)14-21(29)26-20-8-6-18(7-9-20)23-25-15-33-27-23/h3-9,15,19H,10-14H2,1-2H3,(H,26,29)

Physicochemical Descriptors

Property Name Value
Molecular Formula C24H26N4O5S
Molecular Weight 482.56
AlogP 3.15
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 6.0
Polar Surface Area 122.47
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 34.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Helicase primate complex inhibitor PMDA PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Herpes Zoster 3 D006562 ClinicalTrials
Herpes Simplex 3 D006561 ClinicalTrials
Herpes Genitalis 2 D006558 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4297592
DrugBank DB11701
DrugCentral 5266
FDA SRS 94X46KW4AE
PubChem 11397521
SureChEMBL SCHEMBL2238614
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