CANFOSFAMIDE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 1RS284BFUI

Structure
InChI Key OJLHWPALWODJPQ-QNWVGRARSA-N
Smile N[C@@H](CCC(=O)N[C@@H](CS(=O)(=O)CCOP(=O)(N(CCCl)CCCl)N(CCCl)CCCl)C(=O)N[C@@H](C(=O)O)c1ccccc1)C(=O)O
InChI
InChI=1S/C26H40Cl4N5O10PS/c27-8-12-34(13-9-28)46(42,35(14-10-29)15-11-30)45-16-17-47(43,44)18-21(32-22(36)7-6-20(31)25(38)39)24(37)33-23(26(40)41)19-4-2-1-3-5-19/h1-5,20-21,23H,6-18,31H2,(H,32,36)(H,33,37)(H,38,39)(H,40,41)/t20-,21-,23+/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C26H40Cl4N5O10PS
Molecular Weight 787.48
AlogP 1.7
Hydrogen Bond Acceptor 9.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 25.0
Polar Surface Area 225.74
Molecular species ZWITTERION
Aromatic Rings 1.0
Heavy Atoms 47.0

Pharmacology

Action Mechanism of Action Reference
DISRUPTING AGENT DNA disrupting agent PubMed Other

Cross References

Resources Reference
ChEBI 135883
ChEMBL CHEMBL2111086
DrugBank DB04972
DrugCentral 3062
FDA SRS 1RS284BFUI
PubChem 5312109
SureChEMBL SCHEMBL4914495
ZINC ZINC000085537051
CONTENTS