| Synonyms: | |
| Status: | Approved |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| ATC: | B05XB03 |
| UNII: | K3Z4F929H6 |
Structure
| InChI Key | KDXKERNSBIXSRK-YFKPBYRVSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C6H14N2O2 |
| Molecular Weight | 146.19 |
| AlogP | -0.47 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 89.34 |
| Molecular species | ZWITTERION |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 10.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| None | Radioprotective agent | EMA |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Oxidoreductase
|
- | 61200 | - | 54600 | - | |
|
Enzyme
|
- | 61200 | - | 54600 | 50 | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC03 and SLC07 families of heteromeric amino acid transporters (HATs)
SLC07 Cationic amino acid transporter/glycoprotein-associated family
|
- | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Myocardial Infarction | 2 | D009203 | ClinicalTrials |
| Diabetes Mellitus, Type 2 | 1 | D003924 | ClinicalTrials |
| Prediabetic State | 1 | D011236 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 133538 |
| ChEMBL | CHEMBL8085 |
| DrugBank | DB00123 |
| DrugCentral | 1622 |
| EPA CompTox | DTXSID6023232 |
| FDA SRS | K3Z4F929H6 |
| Human Metabolome Database | HMDB0000182 |
| Guide to Pharmacology | 724 |
| KEGG | C00047 |
| PharmGKB | PA450280 |
| PubChem | 5962 |
| SureChEMBL | SCHEMBL1646 |
| ZINC | ZINC000001532522 |
CONTENTS