CLOTIAZEPAM

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Synonyms:	Clotiazepam Clozan
Status:	Approved
Entry Type:	Small molecule
Molecule Category:	UNKNOWN
ATC:	N05BA21
UNII:	ZCN055599V

Structure


InChI Key	CHBRHODLKOZEPZ-UHFFFAOYSA-N
Smile	CCc1cc2c(s1)N(C)C(=O)CN=C2c1ccccc1Cl
InChI	InChI=1S/C16H15ClN2OS/c1-3-10-8-12-15(11-6-4-5-7-13(11)17)18-9-14(20)19(2)16(12)21-10/h4-8H,3,9H2,1-2H3

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C16H15ClN2OS
Molecular Weight	318.83
AlogP	3.78
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	0.0
Number of Rotational Bond	2.0
Polar Surface Area	32.67
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	21.0

Pharmacology

Action	Mechanism of Action	Reference
POSITIVE ALLOSTERIC MODULATOR	GABA-A receptor; anion channel positive allosteric modulator	PubMed PubMed

Indications

Mesh Heading	Maximum Phase	Mesh ID	Reference

Related Entries

Scaffolds

Target Level :

Level 3

Level 4

Level 5

Level 6

Extend network:

Indication

Mechanism of Action

Primary Target

Target Level

Cross References

Resources	Reference
ChEBI	31425
ChEMBL	CHEMBL1697737
DrugBank	DB01559
DrugCentral	718
EPA CompTox	DTXSID0022852
FDA SRS	ZCN055599V
Human Metabolome Database	HMDB0015512
PharmGKB	PA164752437
PubChem	2811
SureChEMBL	SCHEMBL44592
ZINC	ZINC000000001207

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