ETIDOCAINE

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Synonyms:	Duranest [as hydrochloride] Etidocaine W-19053 W-19053 [AS HYDROCHLORIDE]
Status:	Approved (1976)
Entry Type:	Small molecule
Molecule Category:	UNKNOWN
ATC:	N01BB07
UNII:	K9D2CE52PU

Structure


InChI Key	VTUSIVBDOCDNHS-UHFFFAOYSA-N
Smile	CCCN(CC)C(CC)C(=O)Nc1c(C)cccc1C
InChI	InChI=1S/C17H28N2O/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5/h9-11,15H,6-8,12H2,1-5H3,(H,18,20)

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C17H28N2O
Molecular Weight	276.42
AlogP	3.75
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	7.0
Polar Surface Area	32.34
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	20.0

Pharmacology

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Ion channel Voltage-gated ion channel Potassium channels Two-pore domain potassium channel	-	39000	-	-	-
Ion channel Voltage-gated ion channel Voltage-gated sodium channel	-	3500	-	-	73

Cross References

Resources	Reference
ChEBI	4904
ChEMBL	CHEMBL492
DrugBank	DB08987
DrugCentral	1097
EPA CompTox	DTXSID1023027
FDA SRS	K9D2CE52PU
Guide to Pharmacology	2621
KEGG	C07530
PubChem	37497
SureChEMBL	SCHEMBL57261

CONTENTS