RETAGLIPTIN

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 328C4R3P9L

Structure
InChI Key WIIAMRXFUJLYEF-SNVBAGLBSA-N
Smile COC(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F)CC2
InChI
InChI=1S/C19H18F6N4O3/c1-32-17(31)16-14-8-28(2-3-29(14)18(27-16)19(23,24)25)15(30)6-10(26)4-9-5-12(21)13(22)7-11(9)20/h5,7,10H,2-4,6,8,26H2,1H3/t10-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H18F6N4O3
Molecular Weight 464.37
AlogP 2.41
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 90.45
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 32.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetes Mellitus, Type 2 3 D003924 ClinicalTrials
Renal Insufficiency 1 D051437 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4297435
DrugBank DB14898
FDA SRS 328C4R3P9L
PubChem 44193830
SureChEMBL SCHEMBL193599
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